The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.
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Base Excision Repair, a Pathway Regulated by Posttranslational ModificationsAtaxin-3 promotes genome integrity by stabilizing Chk1.Ataxin-3, DNA damage repair, and SCA3 cerebellar degeneration: on the path to parsimony?Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate InflammationThe deubiquitinase ataxin-3 requires Rad23 and DnaJ-1 for its neuroprotective role in Drosophila melanogaster.Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genesAntisense oligonucleotide-mediated exon skipping as a strategy to reduce proteolytic cleavage of ataxin-3.Allele-selective suppression of mutant genes in polyglutamine diseases.Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation.Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?Interaction of the polyglutamine protein ataxin-3 with Rad23 regulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3.Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic diseaseAtaxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4.XRCC1-mediated repair of strand breaks independent of PNKP binding.Polyglutamine spinocerebellar ataxias - from genes to potential treatments.On the distribution of intranuclear and cytoplasmic aggregates in the brainstem of patients with spinocerebellar ataxia type 2 and 3.The central role of DNA damage and repair in CAG repeat diseases.Microcephalic primordial dwarfism in an Emirati patient with PNKP mutation.
P2860
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P2860
The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.
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2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
The role of the mammalian DNA ...... ar ataxia type 3 pathogenesis.
@ast
The role of the mammalian DNA ...... ar ataxia type 3 pathogenesis.
@en
type
label
The role of the mammalian DNA ...... ar ataxia type 3 pathogenesis.
@ast
The role of the mammalian DNA ...... ar ataxia type 3 pathogenesis.
@en
prefLabel
The role of the mammalian DNA ...... ar ataxia type 3 pathogenesis.
@ast
The role of the mammalian DNA ...... ar ataxia type 3 pathogenesis.
@en
P2093
P2860
P50
P1433
P1476
The role of the mammalian DNA ...... ar ataxia type 3 pathogenesis.
@en
P2093
Andreia Neves-Carvalho
Anirban Chakraborty
Arnulf H Koeppen
Arpita Chatterjee
Istvan Boldogh
Partha S Sarkar
Raj K Pandita
Saikat Saha
Santi M Mandal
Tapas K Hazra
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004749
P577
2015-01-29T00:00:00Z