Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3.
about
Protective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study.Role of Drug Metabolism in the Cytotoxicity and Clinical Efficacy of Anthracyclines.Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters.Metabolic carbonyl reduction of anthracyclines - role in cardiotoxicity and cancer resistance. Reducing enzymes as putative targets for novel cardioprotective and chemosensitizing agents.Transcriptional regulation of the canine carbonyl reductase 1 gene (cbr1) by the specificity protein 1 (Sp1).CBR3 reduces DOX to DOXOLElevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice.
P2860
Q36245459-A12B8EC8-8E7F-4C40-B811-742F7187A853Q38576762-5127938B-3C49-4A67-9604-5FFE8C6497C8Q38869922-CE7675A5-6CC6-4298-A081-78CDB8ADFE38Q38913918-98D0EA92-8508-4534-9AD9-BED262C60E05Q39507155-39FF8DAF-A5E1-4B66-B79E-9DCB58C854A5Q50295345-28197330-B286-4C45-901B-749B6BC874B7Q55385168-95B47084-F650-4860-AD8E-D627E0342A17
P2860
Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Metabolism of doxorubicin to t ...... role for carbonyl reductase 3.
@ast
Metabolism of doxorubicin to t ...... role for carbonyl reductase 3.
@en
type
label
Metabolism of doxorubicin to t ...... role for carbonyl reductase 3.
@ast
Metabolism of doxorubicin to t ...... role for carbonyl reductase 3.
@en
prefLabel
Metabolism of doxorubicin to t ...... role for carbonyl reductase 3.
@ast
Metabolism of doxorubicin to t ...... role for carbonyl reductase 3.
@en
P2093
P2860
P1476
Metabolism of doxorubicin to t ...... role for carbonyl reductase 3.
@en
P2093
Christopher M Schaupp
Collin C White
Gary F Merrill
Terrance J Kavanagh
P2860
P304
P356
10.1016/J.CBI.2014.11.010
P577
2014-11-21T00:00:00Z