A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.
about
Adaptations of the Secretome of Candida albicans in Response to Host-Related Environmental ConditionsCharacterization of agglutinin-like sequence genes from non-albicans Candida and phylogenetic analysis of the ALS familyCandida albicans possesses Sap7 as a pepstatin A-insensitive secreted aspartic proteaseDictyostelium discoideum as a Novel Host System to Study the Interaction between Phagocytes and YeastsGene overexpression/suppression analysis of candidate virulence factors of Candida albicans.Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans.the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritinA novel immune evasion strategy of candida albicans: proteolytic cleavage of a salivary antimicrobial peptide.Antigenic and phenotypic variations in fungiOverexpression of a dominant-negative allele of SEC4 inhibits growth and protein secretion in Candida albicansRapid detection of Candida albicans in clinical samples by DNA amplification of common regions from C. albicans-secreted aspartic proteinase genes.Candida albicans virulence and drug-resistance requires the O-acyltransferase Gup1p.Host cell invasion and virulence mediated by Candida albicans Ssa1.Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasisSecreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells.Candida albicans-secreted aspartic proteinases modify the epithelial cytokine response in an in vitro model of vaginal candidiasisPotential role of phospholipases in virulence and fungal pathogenesis.Candida infections of the genitourinary tract.Induction of the Candida albicans filamentous growth program by relief of transcriptional repression: a genome-wide analysisIn vivo analysis of secreted aspartyl proteinase expression in human oral candidiasisIn Vivo Indicators of Cytoplasmic, Vacuolar, and Extracellular pH Using pHluorin2 in Candida albicans.Unanticipated heterogeneity in growth rate and virulence among Candida albicans AAF1 null mutants.Enhanced extracellular production of aspartyl proteinase, a virulence factor, by Candida albicans isolates following growth in subinhibitory concentrations of fluconazole.Germ tubes and proteinase activity contribute to virulence of Candida albicans in murine peritonitisRepression of hyphal proteinase expression by the mitogen-activated protein (MAP) kinase phosphatase Cpp1p of Candida albicans is independent of the MAP kinase Cek1p.Cell wall and secreted proteins of Candida albicans: identification, function, and expressionInduction of SAP7 correlates with virulence in an intravenous infection model of candidiasis but not in a vaginal infection model in miceTranscriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infectionDisruption of the Candida albicans TPS2 gene encoding trehalose-6-phosphate phosphatase decreases infectivity without affecting hypha formation.Lipid raft polarization contributes to hyphal growth in Candida albicansSecreted aspartic protease cleavage of Candida albicans Msb2 activates Cek1 MAPK signaling affecting biofilm formation and oropharyngeal candidiasis.Cell cycle-independent phospho-regulation of Fkh2 during hyphal growth regulates Candida albicans pathogenesis.The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium.Host cell invasion in mucormycosis: role of ironCandida albicans secreted aspartyl proteinases in virulence and pathogenesisCoevolution of morphology and virulence in Candida species.Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.Inactivation of the antifungal and immunomodulatory properties of human cathelicidin LL-37 by aspartic proteases produced by the pathogenic yeast Candida albicans.Disruption of the subtilase gene, albin1, in Ophiostoma piliferumTranscriptomic analysis of vulvovaginal candidiasis identifies a role for the NLRP3 inflammasome.
P2860
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P2860
A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.
description
1997 nî lūn-bûn
@nan
1997 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A triple deletion of the secre ...... s causes attenuated virulence.
@ast
A triple deletion of the secre ...... s causes attenuated virulence.
@en
type
label
A triple deletion of the secre ...... s causes attenuated virulence.
@ast
A triple deletion of the secre ...... s causes attenuated virulence.
@en
prefLabel
A triple deletion of the secre ...... s causes attenuated virulence.
@ast
A triple deletion of the secre ...... s causes attenuated virulence.
@en
P2093
P2860
P1476
A triple deletion of the secre ...... ns causes attenuated virulence
@en
P2093
P2860
P304
P407
P577
1997-09-01T00:00:00Z