Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice. - Wikidata - wikimedia - TriplyDB

Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice.

Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice.

http://www.wikidata.org/entity/Q35556560

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The search for novel analgesics: targets and mechanisms Roads Less Traveled: Sexual Dimorphism and Mast Cell Contributions to Migraine Pathology Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics Opioid-induced central immune signaling: implications for opioid analgesia Glial contributions to visceral pain: implications for disease etiology and the female predominance of persistent pain Glucuronic acid and the ethanol metabolite ethyl-glucuronide cause toll-like receptor 4 activation and enhanced pain Carbamazepine potentiates the effectiveness of morphine in a rodent model of neuropathic pain Animal models of chronic pain: Advances and challenges for clinical translation.Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury.Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4.Toll-like receptor 4 contributes to chronic itch, alloknesis, and spinal astrocyte activation in male mice Stat3 inhibition attenuates mechanical allodynia through transcriptional regulation of chemokine expression in spinal astrocytes.The anatomical distribution of trigeminal neuralgia: a perspective and future directions.Toll-like receptor 4 mutant and null mice retain morphine-induced tolerance, hyperalgesia, and physical dependence.Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy.Androgen receptor transcriptionally regulates μ-opioid receptor expression in rat trigeminal ganglia.Spinal inhibition of p38 MAP kinase reduces inflammatory and neuropathic pain in male but not female mice: Sex-dependent microglial signaling in the spinal cord.Tanshinone IIA Downregulates HMGB1 and TLR4 Expression in a Spinal Nerve Ligation Model of Neuropathic Pain.BDNF released during neuropathic pain potentiates NMDA receptors in primary afferent terminals The conditioned place preference test for assessing welfare consequences and potential refinements in a mouse bladder cancer model.Inflammation and inflammatory control in interstitial cystitis/bladder pain syndrome: Associations with painful symptoms.Influence of intrathecal delivery of bone marrow-derived mesenchymal stem cells on spinal inflammation and pain hypersensitivity in a rat model of peripheral nerve injury.Inhibition of Inflammatory and Neuropathic Pain by Targeting a Mu Opioid Receptor/Chemokine Receptor5 Heteromer (MOR-CCR5).TNFα levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine Activation of toll like receptor 4 attenuates GABA synthesis and postsynaptic GABA receptor activities in the spinal dorsal horn via releasing interleukin-1 beta.Paclitaxel induces acute pain via directly activating toll like receptor 4 Sex differences in experimental measures of pain sensitivity and endogenous pain inhibition.TLR4 upregulates CBS expression through NF-κB activation in a rat model of irritable bowel syndrome with chronic visceral hypersensitivity.Toll-like receptor 4 signaling in neurons of trigeminal ganglion contributes to nociception induced by acute pulpitis in rats.Emerging role of Toll-like receptors in the control of pain and itch.Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity Toll-like receptor 4 and comorbid pain in Interstitial Cystitis/Bladder Pain Syndrome: a multidisciplinary approach to the study of chronic pelvic pain research network study Sex, drugs and pain control Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia.Inhibition of the Rho/Rho kinase pathway prevents lipopolysaccharide-induced hyperalgesia and the release of TNF-α and IL-1β in the mouse spinal cord.Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in Sprague-Dawley rats.Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model.Quantification of pain in sickle mice using facial expressions and body measurements.Differences in cisplatin-induced mechanical allodynia in male and female mice.Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia.

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P2860

Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice.

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JNEUROSCI.3859-11.2011

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Alexander H Tuttle

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Allyson C Graham

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Jean-Sebastien Austin

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Jeffrey S Mogil

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Jennifer Ritchie

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Lucas Topham

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Michael L LaCroix-Fralish

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Michael W Salter

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Mona Lisa Chanda

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Robert E Sorge

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P2860

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans

Quantitative assessment of tactile allodynia in the rat paw

Down-regulation of Toll-like receptor 4 gene expression by short interfering RNA attenuates bone cancer pain in a rat model

Studying sex and gender differences in pain and analgesia: a consensus report.

The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy.

Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain.

Spinal toll like receptor 3 is involved in chronic pancreatitis-induced mechanical allodynia of rat

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway.

The case for the inclusion of female subjects in basic science studies of pain.

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10.1523/JNEUROSCI.3859-11.2011

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Toll-like receptor

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