Long-term regulated expression of growth hormone in mice after intramuscular gene transfer
about
A gene expression system offering multiple levels of regulation: the Dual Drug Control (DDC) systemTransgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primatesA time- and dose-dependent STAT1 expression system.Vector and helper genome rearrangements occur during production of helper-dependent adenoviral vectors.PiggyBac transposon-based inducible gene expression in vivo after somatic cell gene transfer.Impaired intracellular trafficking of adeno-associated virus type 2 vectors limits efficient transduction of murine fibroblasts.Gene therapy in the CNS.Regulated gene expression systems.The potential of adeno-associated viral vectors for gene delivery to muscle tissue.Ecdysone-controlled expression of transgenes.Regulated gene expression in gene therapy.Regulated production of proteins from muscle using gene transfer: potential therapeutic applications.Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glandsGene therapy approaches for bone regeneration.Intravenous AAV8 Encoding Urocortin-2 Increases Function of the Failing Heart in Mice.Improved function of the failing rat heart by regulated expression of insulin-like growth factor I via intramuscular gene transfer.Optimizing regulatable gene expression using adenoviral vectors.Vitamin H-regulated transgene expression in mammalian cells.Biological approaches to bone regeneration by gene therapy.Long-term and stable correction of uremic anemia by intramuscular injection of plasmids containing hypoxia-regulated system of erythropoietin expression.Enhancing the utility of adeno-associated virus gene transfer through inducible tissue-specific expression.Intravenous adeno-associated virus serotype 8 encoding urocortin-2 provides sustained augmentation of left ventricular function in mice.Delivery of a stringent dimerizer-regulated gene expression system in a single retroviral vectorEngineered fibroblast growth factor 19 reduces liver injury and resolves sclerosing cholangitis in Mdr2-deficient mice.Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle.Spatiotemporal control of vascular endothelial growth factor expression using a heat-shock-activated, rapamycin-dependent gene switch.Allosteric activation of kinases: design and application of RapR kinases.Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus.A new hybrid system capable of efficient lentiviral vector production and stable gene transfer mediated by a single helper-dependent adenoviral vectorGene therapy for long-term restoration of circulating thymulin in thymectomized mice and rats.Gene therapy of ovarian cancer with IFN-alpha-producing fibroblasts: comparison of constitutive and inducible vectors.Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor.Rapamycin control of exocrine protein levels in saliva after adenoviral vector-mediated gene transfer.Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector.Partial rescue of growth failure in growth hormone (GH)-deficient mice by a single injection of a double-stranded adeno-associated viral vector expressing the GH gene driven by a muscle-specific regulatory cassette.Pharmacologically regulated gene expression in the retina following transduction with viral vectors.Constitutive and regulated expression of processed insulin following in vivo hepatic gene transfer.Optimization and direct comparison of the dimerizer and reverse tet transcriptional control systems.Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.Tetracycline-inducible transgene expression mediated by a single AAV vector.
P2860
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P2860
Long-term regulated expression of growth hormone in mice after intramuscular gene transfer
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Long-term regulated expression ...... er intramuscular gene transfer
@ast
Long-term regulated expression ...... er intramuscular gene transfer
@en
type
label
Long-term regulated expression ...... er intramuscular gene transfer
@ast
Long-term regulated expression ...... er intramuscular gene transfer
@en
prefLabel
Long-term regulated expression ...... er intramuscular gene transfer
@ast
Long-term regulated expression ...... er intramuscular gene transfer
@en
P2093
P2860
P356
P1476
Long-term regulated expression ...... er intramuscular gene transfer
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.15.8657
P407
P577
1999-07-01T00:00:00Z