How structural and physicochemical determinants shape sequence constraints in a functional enzyme
about
Causes of evolutionary rate variation among protein sitesFunctional Sites Induce Long-Range Evolutionary Constraints in EnzymesDissecting the roles of local packing density and longer-range effects in protein sequence evolutionDetection and sequence/structure mapping of biophysical constraints to protein variation in saturated mutational libraries and protein sequence alignments with a dedicated serverMolecular Effects of Concentrated Solutes on Protein Hydration, Dynamics, and Electrostatics.Molecular Determinants of Mutant Phenotypes, Inferred from Saturation Mutagenesis DataCoevolutionary Landscape Inference and the Context-Dependence of Mutations in Beta-Lactamase TEM-1.The Structure of a Thermophilic Kinase Shapes Fitness upon Random Circular PermutationExtensively Parameterized Mutation-Selection Models Reliably Capture Site-Specific Selective Constraint.Structural, physicochemical and dynamic features conserved within the aerolysin pore-forming toxin family.Assessment of hard target modeling in CASP12 reveals an emerging role of alignment-based contact prediction methods.Alternative evolutionary histories in the sequence space of an ancient protein.Optimization of Conformational Dynamics in an Epistatic Evolutionary Trajectory.
P2860
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P2860
How structural and physicochemical determinants shape sequence constraints in a functional enzyme
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
How structural and physicochem ...... traints in a functional enzyme
@ast
How structural and physicochem ...... traints in a functional enzyme
@en
type
label
How structural and physicochem ...... traints in a functional enzyme
@ast
How structural and physicochem ...... traints in a functional enzyme
@en
prefLabel
How structural and physicochem ...... traints in a functional enzyme
@ast
How structural and physicochem ...... traints in a functional enzyme
@en
P2093
P2860
P1433
P1476
How structural and physicochem ...... traints in a functional enzyme
@en
P2093
Luciano A Abriata
Matteo Dal Peraro
Timothy Palzkill
P2860
P304
P356
10.1371/JOURNAL.PONE.0118684
P407
P577
2015-02-23T00:00:00Z