The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression.
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Functions and mechanisms of long noncoding RNAs in lung cancerLong Non-coding RNAs and Their Roles in Non-small-cell Lung CancerMolecular and Cellular Mechanisms of Action of Tumour Suppressor GAS5 LncRNALong non-coding RNAs in anti-cancer drug resistanceEmerging roles of Nrf2 signal in non-small cell lung cancerCirculating lncRNAs associated with occurrence of colorectal cancer progression.NLK functions to maintain proliferation and stemness of NSCLC and is a target of metforminLncRNA-GAS5 induces PTEN expression through inhibiting miR-103 in endometrial cancer cells.Metformin sensitizes sorafenib to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse modelsLncDisease: a sequence based bioinformatics tool for predicting lncRNA-disease associations.The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells.LncRNA GAS5 is a critical regulator of metastasis phenotype of melanoma cells and inhibits tumor growth in vivo.Klotho, an anti-aging gene, acts as a tumor suppressor and inhibitor of IGF-1R signaling in diffuse large B cell lymphoma.Uncovering the roles of long non-coding RNAs in cancer stem cells.Loss of long noncoding RNA FOXF1-AS1 regulates epithelial-mesenchymal transition, stemness and metastasis of non-small cell lung cancer cells.Influence of microRNAs and Long Non-Coding RNAs in Cancer Chemoresistance.The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers.Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis.The Regulatory Role of Long Noncoding RNAs in Cancer Drug Resistance.AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.Long Non-Coding RNAs: Key Regulators of Epithelial-Mesenchymal Transition, Tumour Drug Resistance and Cancer Stem Cells.Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy?Histone code and long non-coding RNAs (lncRNAs) aberrations in lung cancer: implications in the therapy response.Genetic polymorphisms of long non-coding RNA GAS5 predict platinum-based concurrent chemoradiotherapy response in nasopharyngeal carcinoma patientsEpigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients.Systematic review and meta-analysis of the utility of long non-coding RNA GAS5 as a diagnostic and prognostic cancer biomarker.Long non-coding RNA AB209630 suppresses cell proliferation and metastasis in human hepatocellular carcinoma.The resistance mechanisms and treatment strategies for EGFR-mutant advanced non-small-cell lung cancer.Prognostic Values of Long Noncoding RNA GAS5 in Various Carcinomas: An Updated Systematic Review and Meta-Analysis.The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer.From biomarkers to therapeutic targets-the promises and perils of long non-coding RNAs in cancer.High glucose contributes to the proliferation and migration of non-small cell lung cancer cells via GAS5-TRIB3 axis.In Silico and In Vitro Analyses of LncRNAs as Potential Regulators in the Transition from the Epithelioid to Sarcomatoid Histotype of Malignant Pleural Mesothelioma (MPM).Role of long non-coding RNA in drug resistance in non-small cell lung cancer.A simple method to assess in vivo proliferation in lung vasculature with EdU: the case of MMC-induced PVOD in rat.The long noncoding RNA GAS5 negatively regulates the adipogenic differentiation of MSCs by modulating the miR-18a/CTGF axis as a ceRNA.The long non-coding RNA SNHG5 regulates gefitinib resistance in lung adenocarcinoma cells by targetting /CASP1 axisThe Network of Non-coding RNAs in Cancer Drug ResistanceCombined treatment with metformin and gefitinib overcomes primary resistance to EGFR-TKIs with EGFR mutation via targeting IGF-1R signaling pathway
P2860
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P2860
The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The long non-coding RNA, GAS5, ...... tion of the IGF-1R expression.
@ast
The long non-coding RNA, GAS5, ...... tion of the IGF-1R expression.
@en
type
label
The long non-coding RNA, GAS5, ...... tion of the IGF-1R expression.
@ast
The long non-coding RNA, GAS5, ...... tion of the IGF-1R expression.
@en
prefLabel
The long non-coding RNA, GAS5, ...... tion of the IGF-1R expression.
@ast
The long non-coding RNA, GAS5, ...... tion of the IGF-1R expression.
@en
P2093
P2860
P1476
The long non-coding RNA, GAS5, ...... tion of the IGF-1R expression.
@en
P2093
Mingrui Shao
Shize Yang
Siyuan Dong
Xiaohan Qu
Xinwen Zhong
Xitao Chen
P2860
P2888
P356
10.1186/S13045-015-0140-6
P577
2015-04-29T00:00:00Z
P5875
P6179
1000628745