Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice - Wikidata - wikimedia - TriplyDB

Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

http://www.wikidata.org/entity/Q35574809

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Skeletal stem cells and their contribution to skeletal fragility: senescence and rejuvenation AMP-activated protein kinase reduces inflammatory responses and cellular senescence in pulmonary emphysema Senotherapy: growing old and staying young?Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans.Elimination of p19(ARF)-expressing cells enhances pulmonary function in mice.In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state.Reversal of phenotypes of cellular senescence by pan-mTOR inhibition.Sav1 Loss Induces Senescence and Stat3 Activation Coinciding with Tubulointerstitial Fibrosis.A Quiescent Bcl11b High Stem Cell Population Is Required for Maintenance of the Mammary Gland.Tubular Cell Senescence in the Donated Kidney Predicts Allograft Function, but Not Donor Remnant Kidney Function, in Living Donor Kidney Transplantation.Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells.Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle.

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Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

http://www.wikidata.org/entity/Q35574809

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

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Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

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type

label

Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

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Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

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prefLabel

Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

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Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

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Nature Communications

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Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice

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Aki Hanyu

http://www.w3.org/2001/XMLSchema#string

Akiko Takahashi

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Eiji Hara

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Hiroaki Kanda

http://www.w3.org/2001/XMLSchema#string

Kimi Yamakoshi

http://www.w3.org/2001/XMLSchema#string

Naoko Ohtani

http://www.w3.org/2001/XMLSchema#string

Saburo Sone

http://www.w3.org/2001/XMLSchema#string

Seidai Sato

http://www.w3.org/2001/XMLSchema#string

Yasuhiko Nishioka

http://www.w3.org/2001/XMLSchema#string

Yoshinori Imai

http://www.w3.org/2001/XMLSchema#string

P2860

Cellular and connective tissue changes in alveolar septal walls in emphysema

Association of human aging with a functional variant of klotho.

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways.

Suppression of aging in mice by the hormone Klotho

Klotho and aging

Differential expression of E-cadherin, N-cadherin and beta-catenin in proximal and distal segments of the rat nephron.

The hallmarks of aging

Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system

KLOTHO gene polymorphisms G-395A and C1818T are associated with lipid and glucose metabolism, bone mineral density and systolic blood pressure in Japanese healthy subjects

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7035

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scholarly article

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10.1038/NCOMMS8035

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6

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Hiroyuki Sorimachi

Masaki Takasugi

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2015-04-29T00:00:00Z

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275660577

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25923845

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4421814

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