Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons
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Progressive degeneration of human neural stem cells caused by pathogenic LRRK2Role of Intermediate Filaments in Vesicular TrafficNuclear assembly as a target for anti-cancer therapiesThe nuclear lamina is mechano-responsive to ECM elasticity in mature tissueThe nuclear envelope: an intriguing focal point for neurogenetic diseaseLamin B1 protein is required for dendrite development in primary mouse cortical neuronsLINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retinaImplications and Assessment of the Elastic Behavior of Lamins in LaminopathiesNuclear envelope: positioning nuclei and organizing synapsesLamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in miceIs LMNB1 a susceptibility gene for neural tube defects in humans?Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration.Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2.Lamin B1 is required for mature neuron-specific gene expression during olfactory sensory neuron differentiation.Lamin B1 levels modulate differentiation into neurons during embryonic corticogenesisNuclear lamins and neurobiology.Nuclear envelope protein MAN1 regulates clock through BMAL1Do lamin B1 and lamin B2 have redundant functions?The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration.Inner nuclear membrane proteins: impact on human disease.An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatinAccessorizing and anchoring the LINC complex for multifunctionality.FGF signalling regulates chromatin organisation during neural differentiation via mechanisms that can be uncoupled from transcriptionNuclear envelope in nuclear positioning and cell migrationRole of lamin b1 in chromatin instabilityMice that express farnesylated versions of prelamin A in neurons develop achalasia.Stress sensitivity and mechanotransduction during heart developmentThe role of nuclear lamin B1 in cell proliferation and senescence.Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA.Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation.Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cellsAre B-type lamins essential in all mammalian cells?The functions of the nuclear envelope in mediating the molecular crosstalk between the nucleus and the cytoplasm.Sun1 deficiency leads to cerebellar ataxia in miceUnderstanding the roles of nuclear A- and B-type lamins in brain development.The mevalonate pathway regulates primitive streak formation via protein farnesylationLamins in development, tissue maintenance and stress.Nuclear lamins in the brain - new insights into function and regulation.Lamin A tail modification by SUMO1 is disrupted by familial partial lipodystrophy-causing mutationsLamin A/C is expressed in pluripotent mouse embryonic stem cells.
P2860
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P2860
Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Deficiencies in lamin B1 and l ...... shape abnormalities in neurons
@ast
Deficiencies in lamin B1 and l ...... shape abnormalities in neurons
@en
type
label
Deficiencies in lamin B1 and l ...... shape abnormalities in neurons
@ast
Deficiencies in lamin B1 and l ...... shape abnormalities in neurons
@en
prefLabel
Deficiencies in lamin B1 and l ...... shape abnormalities in neurons
@ast
Deficiencies in lamin B1 and l ...... shape abnormalities in neurons
@en
P2093
P2860
P356
P1476
Deficiencies in lamin B1 and l ...... shape abnormalities in neurons
@en
P2093
Catherine Coffinier
Chika Nobumori
Hea-Jin Jung
Karen Reue
Loren G Fong
Pieter J de Jong
Richard H Barnes
Sandy Chang
Yuko Yoshinaga
P2860
P304
P356
10.1091/MBC.E11-06-0504
P577
2011-10-05T00:00:00Z