Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. - Wikidata - wikimedia - TriplyDB

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

http://www.wikidata.org/entity/Q35583640

about

Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP Processing of microRNA primary transcripts requires heme in mammalian cells Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer The insights of Let-7 miRNAs in oncogenesis and stem cell potency Lin28 and let-7 in cell metabolism and cancer RNA-Binding Proteins in the Regulation of miRNA Activity: A Focus on Neuronal Functions The network of pluripotency, epithelial-mesenchymal transition, and prognosis of breast cancer MicroRNAs and triple negative breast cancer Tumor suppressor microRNAs: a novel non-coding alliance against cancer microRNAs as novel regulators of stem cell pluripotency and somatic cell reprogramming Regulation of microRNA biogenesis and turnover by animals and their viruses Hepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseases A Genetic Cascade of let-7-ncl-1-fib-1 Modulates Nucleolar Size and rRNA Pool in Caenorhabditis elegans Lin-28 regulates oogenesis and muscle formation in Drosophila melanogaster Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase Outside the coding genome, mammalian microRNAs confer structural and functional complexity Focal DNA copy number changes in neuroblastoma target MYCN regulated genes Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis Lin28: primal regulator of growth and metabolism in stem cells Suppression of MicroRNA-7 (miR-7) Biogenesis by Nuclear Factor 90-Nuclear Factor 45 Complex (NF90-NF45) Controls Cell Proliferation in Hepatocellular Carcinoma Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers Exposure to endocrine disruptor induces transgenerational epigenetic deregulation of microRNAs in primordial germ cells Changes in hypothalamic expression of the Lin28/let-7 system and related microRNAs during postnatal maturation and after experimental manipulations of puberty A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma A Lin28 homologue reprograms differentiated cells to stem cells in the moss Physcomitrella patens Oncogenic mechanisms of Lin28 in breast cancer: new functions and therapeutic opportunities.Lin28B expression correlates with aggressive clinicopathological characteristics in breast invasive ductal carcinoma.Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications.Drosha protein levels are translationally regulated during Xenopus oocyte maturation The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome Lin28B is a novel prognostic marker in gastric adenocarcinoma.miR-125b promotes early germ layer specification through Lin28/let-7d and preferential differentiation of mesoderm in human embryonic stem cells.MicroRNAs associated with HBV infection and HBV-related HCC.Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7).Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4).let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis.Genomic DNA copy-number alterations of the let-7 family in human cancers Caenorhabditis elegans period homolog lin-42 regulates the timing of heterochronic miRNA expression.

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P2860

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

http://www.wikidata.org/entity/Q35583640

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

@ast

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

@en

type

label

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

@ast

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

@en

prefLabel

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

@ast

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms.

@en

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J.CELL.2011.10.039

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P1476

Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms

@en

P2093

Charalabos Pothoulakis

http://www.w3.org/2001/XMLSchema#string

Christos Polytarchou

http://www.w3.org/2001/XMLSchema#string

Dimitrios Iliopoulos

http://www.w3.org/2001/XMLSchema#string

Elena Piskounova

http://www.w3.org/2001/XMLSchema#string

James E Thornton

http://www.w3.org/2001/XMLSchema#string

Richard I Gregory

http://www.w3.org/2001/XMLSchema#string

Robert J LaPierre

http://www.w3.org/2001/XMLSchema#string

P2860

Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs

TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

The Microprocessor complex mediates the genesis of microRNAs

LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans

A Yin-Yang balancing act of the lin28/let-7 link in tumorigenesis

Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells

Selective blockade of microRNA processing by Lin28

Regression of murine lung tumors by the let-7 microRNA

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1066-1079

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5

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