Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma. - Wikidata - wikimedia - TriplyDB

Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma.

Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma.

http://www.wikidata.org/entity/Q35586677

about

IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives Deep Learning based Radiomics (DLR) and its usage in noninvasive IDH1 prediction for low grade glioma.Discordant intracellular and plasma D-2-hydroxyglutarate levels in a patient with IDH2 mutated angioimmunoblastic T-cell lymphoma Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma Quantitative Imaging of D-2-Hydroxyglutarate in Selected Histological Tissue Areas by a Novel Bioluminescence Technique.Liquid biopsies in patients with diffuse glioma.Study protocol of a phase IB/II clinical trial of metformin and chloroquine in patients with IDH1-mutated or IDH2-mutated solid tumours Emerging circulating biomarkers in glioblastoma: promises and challenges.Replication Study: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase.Urine 2-Hydroxyglutarate in Glioma.Noninvasive IDH1 mutation estimation based on a quantitative radiomics approach for grade II glioma.Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies.Pharmacodynamics of mutant-IDH1 inhibitors in glioma patients probed by in vivo 3D MRS imaging of 2-hydroxyglutarate.

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P2860

Diagnostic value of plasma and urinary 2-hydroxyglutarate to identify patients with isocitrate dehydrogenase-mutated glioma.

http://www.wikidata.org/entity/Q35586677

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Diagnostic value of plasma and ...... dehydrogenase-mutated glioma.

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Diagnostic value of plasma and ...... dehydrogenase-mutated glioma.

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Diagnostic value of plasma and ...... dehydrogenase-mutated glioma.

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Diagnostic value of plasma and ...... dehydrogenase-mutated glioma.

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Diagnostic value of plasma and ...... dehydrogenase-mutated glioma.

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THEONCOLOGIST.2014-0266

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Diagnostic value of plasma and ...... e dehydrogenase-mutated glioma

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Alessandro Della Puppa

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Ardi Pambuku

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Domenico D'Avella

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Giuseppe Corona

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Luisa Bellu

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Marina Paola Gardiman

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Pasquale Fiduccia

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Roberta Bertorelle

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P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

The 2007 WHO classification of tumours of the central nervous system

IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate.

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.

Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma.

Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism

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562-567

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10.1634/THEONCOLOGIST.2014-0266

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5

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20

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Giuseppe Lombardi

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2015-04-10T00:00:00Z

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274781388

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