Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats. - Wikidata - wikimedia - TriplyDB

Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats.

Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats.

http://www.wikidata.org/entity/Q35588162

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Transcriptional mechanisms of drug addiction Transcriptional and epigenetic mechanisms of addiction Cellular basis of memory for addiction MicroRNAs Modulate Interactions between Stress and Risk for Cocaine Addiction Drug withdrawal conceptualized as a stressor.Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs Decreased Caffeine-Induced Locomotor Activity via Microinjection of CART Peptide into the Nucleus Accumbens Is Linked to Inhibition of the pCaMKIIa-D3R Interaction Enhancement of behavioral sensitization, anxiety-like behavior, and hippocampal and frontal cortical CREB levels following cocaine abstinence in mice exposed to cocaine during adolescence Psychological stress, cocaine and natural reward each induce endoplasmic reticulum stress genes in rat brain FoxO6 regulates memory consolidation and synaptic function Long-lasting impairment of mGluR5-activated intracellular pathways in the striatum after withdrawal of cocaine self-administration CREB activity in dopamine D1 receptor expressing neurons regulates cocaine-induced behavioral effects The snoRNA MBII-52 regulates cocaine-induced conditioned place preference and locomotion in mice Biological substrates of addiction.Environmental enrichment alters protein expression as well as the proteomic response to cocaine in rat nucleus accumbens.Optogenetic stimulation of accumbens shell or shell projections to lateral hypothalamus produce differential effects on the motivation for cocaine Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment Reflections on: "A general role for adaptations in G-Proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function".Translational Research on Nicotine Dependence.Dynamic proteomics of nucleus accumbens in response to acute psychological stress in environmentally enriched and isolated rats κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake.Serum response factor and cAMP response element binding protein are both required for cocaine induction of ΔFosB.Phosphodiesterase 4 inhibition impairs cocaine-induced inhibitory synaptic plasticity and conditioned place preference Current perspectives on the neurobiology of drug addiction: a focus on genetics and factors regulating gene expression.Roles of nucleus accumbens CREB and dynorphin in dysregulation of motivation.Hippocampal neurogenesis protects against cocaine-primed relapse.Nicotine exposure and transgenerational impact: a prospective study on small regulatory microRNAs.The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research.Single nucleotide polymorphism near CREB1, rs7591784, is associated with pretreatment methamphetamine use frequency and outcome of outpatient treatment for methamphetamine use disorder.Emerging targets for addiction neuropharmacology: From mechanisms to therapeutics Escalation of drug self-administration as a hallmark of persistent addiction liability.Transcriptomics of Environmental Enrichment Reveals a Role for Retinoic Acid Signaling in Addiction.Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons.Viral over-expression of D1 dopamine receptors in the prefrontal cortex increase high-risk behaviors in adults: comparison with adolescents Neuroplasticity in addiction: cellular and transcriptional perspectives.BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors.Glycogen synthase kinase 3 beta alters anxiety-, depression-, and addiction-related behaviors and neuronal activity in the nucleus accumbens shell.Thioredoxin-1 was required for CREB activity by methamphetamine in rat pheochromocytoma cells.HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors.Overexpression of the histone dimethyltransferase G9a in nucleus accumbens shell increases cocaine self-administration, stress-induced reinstatement, and anxiety.

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Overexpression of CREB in the nucleus accumbens shell increases cocaine reinforcement in self-administering rats.

http://www.wikidata.org/entity/Q35588162

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Overexpression of CREB in the ...... nt in self-administering rats.

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Overexpression of CREB in the ...... nt in self-administering rats.

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Overexpression of CREB in the ...... nt in self-administering rats.

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JNEUROSCI.3070-11.2011

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Overexpression of CREB in the ...... nt in self-administering rats.

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Caroline E Bass

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Danielle L Graham

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David W Self

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Erin B Larson

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Ernest F Terwilliger

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Joseph Webb

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Nicole Buzin

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Rachael L Neve

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Rose R Arzaga

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Thomas A Green

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P2860

Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins

U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking

Altered responsiveness to cocaine and increased immobility in the forced swim test associated with elevated cAMP response element-binding protein expression in nucleus accumbens

Striatal microRNA controls cocaine intake through CREB signalling

MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212.

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions

The many faces of CREB

cAMP response element binding protein phosphorylation in nucleus accumbens underlies sustained recovery of sensorimotor gating following repeated D₂-like receptor agonist treatment in rats

Appetitive Pavlovian conditioned stimuli increase CREB phosphorylation in the nucleus accumbens

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16447-16457

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10.1523/JNEUROSCI.3070-11.2011

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45

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Eric J. Nestler

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22072694

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3229171

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