Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.
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Melanocortin 1 Receptor: Structure, Function, and RegulationHuman pigmentation genes under environmental selectionMelanocytes as instigators and victims of oxidative stressThe impact of skin colour on human photobiological responsesSignificance of the Melanocortin 1 and Endothelin B Receptors in Melanocyte Homeostasis and Prevention of Sun-Induced GenotoxicityBody pigmentation as a risk factor for the formation of intracranial aneurysms.Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanomaMitochondrial DNA 4977-base pair common deletion in blood leukocytes and melanoma risk.Melanoma genetics.Skin phototype: a new perspective.A melanin-independent interaction between Mc1r and Met signaling pathways is required for HGF-dependent melanomaInherited variation at MC1R and ASIP and association with melanoma-specific survival.Defining the Contribution of MC1R Physiological Ligands to ATR Phosphorylation at Ser435, a Predictor of DNA Repair in MelanocytesMC1R gene variants and non-melanoma skin cancer: a pooled-analysis from the M-SKIP project.Transcriptome Analysis Identifies the Dysregulation of Ultraviolet Target Genes in Human Skin Cancers.AKAP12 mediates PKA-induced phosphorylation of ATR to enhance nucleotide excision repairImpact of the Circadian Clock on UV-Induced DNA Damage Response and Photocarcinogenesis.Cellular and ultrastructural characterization of the grey-morph phenotype in southern right whales (Eubalaena australis).Inherited variants in the MC1R gene and survival from cutaneous melanoma: a BioGenoMEL study.An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin backgroundEpigenetic and genetic dissections of UV-induced global gene dysregulation in skin cells through multi-omics analysesMelanocortin 1 receptor variants: functional role and pigmentary associations.DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.MC1R and NR4A receptors in cellular stress and DNA repair: implications for UVR protection.MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentationCellular Mechanisms of Oxidative Stress and Action in Melanoma.Melanoma-associated GRM3 variants dysregulate melanosome trafficking and cAMP signaling.Syndecan-2 regulates melanin synthesis via protein kinase C βII-mediated tyrosinase activation.Variants of the melanocortin-1 receptor: do they matter clinically?Paracrine regulation of melanocyte genomic stability: a focus on nucleotide excision repair.Association of Melanocortin-1 Receptor Variants with Pigmentary Traits in Humans: A Pooled Analysis from the M-Skip Project.Mechanisms and prevention of UV-induced melanoma.Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors.Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3.Reciprocal responses of fibroblasts and melanocytes to α-MSH depending on MC1R polymorphisms.The melanocortin signaling cAMP axis accelerates repair and reduces mutagenesis of platinum-induced DNA damage.Beyond Red Hair and Sunburns: Uncovering the Molecular Mechanisms of MC1R Signaling and Repair of UV-Induced DNA DamageEffect of MC1R variant allele status on MSH-ligand induction of dopachrome tautomerase in melanocytes co-cultured with keratinocytes.Loci associated with skin pigmentation identified in African populations.The effect of MC1R variants and sunscreen on the response of human melanocytes in vivo to ultraviolet radiation and implications for melanoma.
P2860
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P2860
Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Melanocortin 1 receptor genoty ...... ytes to ultraviolet radiation.
@ast
Melanocortin 1 receptor genoty ...... ytes to ultraviolet radiation.
@en
type
label
Melanocortin 1 receptor genoty ...... ytes to ultraviolet radiation.
@ast
Melanocortin 1 receptor genoty ...... ytes to ultraviolet radiation.
@en
prefLabel
Melanocortin 1 receptor genoty ...... ytes to ultraviolet radiation.
@ast
Melanocortin 1 receptor genoty ...... ytes to ultraviolet radiation.
@en
P2093
P2860
P50
P356
P1433
P1476
Melanocortin 1 receptor genoty ...... cytes to ultraviolet radiation
@en
P2093
Ana Luisa Kadekaro
George Babcock
Pamela Cassidy
Prashiela Manga
Raymond E Boissy
Renny J Kavanagh
Sancy Leachman
Sandy Schwemberger
Viki Swope
Zalfa A Abdel-Malek
P2860
P304
P356
10.1096/FJ.10-158485
P407
P577
2010-06-02T00:00:00Z