Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential. - Wikidata - wikimedia - TriplyDB

Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential.

Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential.

http://www.wikidata.org/entity/Q35589633

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Radioresistance of Brain Tumors Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets Common stemness regulators of embryonic and cancer stem cells The Effect of Hypoxia on Mesenchymal Stem Cell Biology Brain tumor stem cells: Molecular characteristics and their impact on therapy Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells Upregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H⁺ extrusion, cell migration and survival.Cancer stem cell heterogeneity: origin and new perspectives on CSC targeting Hypoxia and regulation of cancer cell stemness.Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling Nrf2 is required to maintain the self-renewal of glioma stem cells.Challenges and opportunities in targeting the menin-MLL interaction.Pharmacological HIF2α inhibition improves VHL disease-associated phenotypes in zebrafish model.Cancer stem cells in glioblastoma Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype EGFR promoter exhibits dynamic histone modifications and binding of ASH2L and P300 in human germinal matrix and gliomas.Hypoxia-regulated target genes implicated in tumor metastasis.Glioblastoma: Defining Tumor Niches.Glioblastoma multiforme: Effect of hypoxia and hypoxia inducible factors on therapeutic approaches Signal transduction molecule patterns indicating potential glioblastoma therapy approaches.Epigenetic regulation in adult stem cells and cancers.Differential Nrf2 expression between glioma stem cells and non-stem-like cells in glioblastoma.Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges.Epigenetic alterations involved in cancer stem cell reprogramming.Critical multiple angiogenic factors secreted by glioblastoma stem-like cells underline the need for combinatorial anti-angiogenic therapeutic strategies.Epigenetic regulation of hypoxia-responsive gene expression: focusing on chromatin and DNA modifications.Epigenetic mechanisms of tumorigenicity manifesting in stem cells.An epigenetic gateway to brain tumor cell identity.Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression.Evaluation of cytotoxic properties of a cyclopamine glucuronide prodrug in rat glioblastoma cells and tumors.Identification of mixed lineage leukemia 1(MLL1) protein as a coactivator of heat shock factor 1(HSF1) protein in response to heat shock protein 90 (HSP90) inhibition.Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications.The ultrastructural difference between CD133-positive U251 glioma stem cells and normal U251 glioma cells.An overview of therapeutic approaches to brain tumor stem cells Inhibitory effects of B-cell lymphoma 2 on the vasculogenic mimicry of hypoxic human glioma cells.Cancer Stem Cells under Hypoxia as a Chemoresistance Factor in Breast and Brain.Epigenetic regulation of NOTCH1 and NOTCH3 by KMT2A inhibits glioma proliferation.On the geometric modeling approach to empirical null distribution estimation for empirical Bayes modeling of multiple hypothesis testing The epigenetic factor Kmt2a/Mll1 regulates neural progenitor proliferation and neuronal and glial differentiation.

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P2860

Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential.

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P2860

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines

The genetic landscape of the childhood cancer medulloblastoma

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

A perivascular niche for brain tumor stem cells

Regulation of MLL1 H3K4 methyltransferase activity by its core components

MLL translocations, histone modifications and leukaemia stem-cell development

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