The utility of animal models to evaluate novel anti-obesity agents.
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Questioning the preclinical paradigm: natural, extreme biology as an alternative discovery platformInhibition of gastric lipase as a mechanism for body weight and plasma lipids reduction in Zucker rats fed a rosemary extract rich in carnosic acidGlomerulosclerosis in the diet-induced obesity model correlates with sensitivity to nitric oxide inhibition but not glomerular hyperfiltration or hypertrophyFeeling the pressure: (patho) physiological mechanisms of weight gain and weight loss in humans.Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet.Characterization of the 5-HT2C receptor agonist lorcaserin on efficacy and safety measures in a rat model of diet-induced obesity.Antihyperglycaemic effect of laser acupuncture treatment at BL20 in diabetic rats.Transgenerational inheritance of metabolic disease.Gut hormones: the future of obesity treatment?Current models and strategies in the development of antiobesity drugs.Anti-obesity drugs: past, present and future.Effects of coconut oil on glycemia, inflammation, and urogenital microbial parameters in female Ossabaw mini-pigs.Translational Modeling to Guide Study Design and Dose Choice in Obesity Exemplified by AZD1979, a Melanin-concentrating Hormone Receptor 1 Antagonist.Dopamine and μ-opioid receptor dysregulation in the brains of binge-eating female rats - possible relevance in the psychopathology and treatment of binge-eating disorder.Investigation of impulsivity in binge-eating rats in a delay-discounting task and its prevention by the d-amphetamine prodrug, lisdexamfetamine.The endocannabinoid system in the baboon (Papio spp.) as a complex framework for developmental pharmacology.Idalopirdine, a selective 5-HT6 receptor antagonist, reduces food intake and body weight in a model of excessive eating.Hypervulnerability of the adolescent prefrontal cortex to nutritional stress via reelin deficiency.Scaffold-free generation of uniform adipose spheroids for metabolism research and drug discovery.Cognitive function is impaired by obesity and alleviated by lorcaserin treatment in mice.Behavioural profile of exendin-4/naltrexone dose combinations in male rats during tests of palatable food consumption.Acute behavioural effects of bupropion and naltrexone, alone and in combination, in non-deprived male rats presented with palatable mash.Low dose naloxone attenuates the pruritic but not anorectic response to rimonabant in male rats.
P2860
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P2860
The utility of animal models to evaluate novel anti-obesity agents.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The utility of animal models to evaluate novel anti-obesity agents.
@ast
The utility of animal models to evaluate novel anti-obesity agents.
@en
type
label
The utility of animal models to evaluate novel anti-obesity agents.
@ast
The utility of animal models to evaluate novel anti-obesity agents.
@en
prefLabel
The utility of animal models to evaluate novel anti-obesity agents.
@ast
The utility of animal models to evaluate novel anti-obesity agents.
@en
P2093
P2860
P1476
The utility of animal models to evaluate novel anti-obesity agents.
@en
P2093
Helen C Jackson
Sharon C Cheetham
Steven P Vickers
P2860
P304
P356
10.1111/J.1476-5381.2011.01245.X
P407
P577
2011-10-01T00:00:00Z