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Drug resistance and cellular adaptation to tumor acidic pH microenvironment

Drug resistance and cellular adaptation to tumor acidic pH microenvironment

http://www.wikidata.org/entity/Q35592647

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Prognostic Significance of Carbonic Anhydrase IX Expression in Cancer Patients: A Meta-Analysis Therapies targeting cancer stem cells: Current trends and future challenges Recapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture Models Engineered Nanoparticles Against MDR in Cancer: The State of the Art and its Prospective.Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors Acidic pH-targeted chitosan capped mesoporous silica coated gold nanorods facilitate detection of pancreatic tumors via multispectral optoacoustic tomography Prognostic value of intratumoral carbonic anhydrase IX expression in testicular germ cell tumors.Hypoxia-induced mobilization of NHE6 to the plasma membrane triggers endosome hyperacidification and chemoresistance.Evolutionary dynamics of carcinogenesis and why targeted therapy does not work.Identification of tumor-specific Salmonella Typhimurium promoters and their regulatory logic.pH and amphiphilic structure direct supramolecular behavior in biofunctional assemblies.Acetate supplementation induces growth arrest of NG2/PDGFRα-positive oligodendroglioma-derived tumor-initiating cells Smart pH-responsive nanocarriers based on nano-graphene oxide for combined chemo- and photothermal therapy overcoming drug resistance.Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance Thyroid hormone and P-glycoprotein in tumor cells.Acidosis Sensing Receptor GPR65 Correlates with Anti-Apoptotic Bcl-2 Family Member Expression in CLL Cells: Potential Implications for the CLL Microenvironment Extracellular low pH affects circadian rhythm expression in human primary fibroblasts.Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1 Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp.HIF-1 at the crossroads of hypoxia, inflammation, and cancer.Extracellular pH Modulates Neuroendocrine Prostate Cancer Cell Metabolism and Susceptibility to the Mitochondrial Inhibitor Niclosamide.The Sulfamate Small Molecule CAIX Inhibitor S4 Modulates Doxorubicin Efficacy.Evidence-based support for the use of proton pump inhibitors in cancer therapy Spontaneously-forming spheroids as an in vitro cancer cell model for anticancer drug screening Advanced targeted nanomedicine Molecular targeting of liposomal nanoparticles to tumor microenvironment.GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironment Dextran-b-poly(L-histidine) copolymer nanoparticles for ph-responsive drug delivery to tumor cells.Pathomimetic cancer avatars for live-cell imaging of protease activity.Targeting the metabolic microenvironment of tumors.Crystalline polymorphism induced by charge regulation in ionic membranes.NaHCO3 enhances the antitumor activities of cytokine-induced killer cells against hepatocellular carcinoma HepG2 cells Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors.Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance.Targeting of crosstalk between tumor and tumor microenvironment by β-D mannuronic acid (M2000) in murine breast cancer model.Regulation and roles of bicarbonate transporters in cancer.A diaCEST MRI approach for monitoring liposomal accumulation in tumors Stimulus-responsive nanopreparations for tumor targeting.

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P2860

Drug resistance and cellular adaptation to tumor acidic pH microenvironment

http://www.wikidata.org/entity/Q35592647

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2011 nî lūn-bûn

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2011年の論文

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2011年论文

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2011年论文

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2011年论文

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name

Drug resistance and cellular adaptation to tumor acidic pH microenvironment

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Drug resistance and cellular adaptation to tumor acidic pH microenvironment

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Drug resistance and cellular adaptation to tumor acidic pH microenvironment

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Drug resistance and cellular adaptation to tumor acidic pH microenvironment

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Molecular Pharmaceutics

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Drug resistance and cellular adaptation to tumor acidic pH microenvironment

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Daniel Verduzco

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Jonathan W Wojtkowiak

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Karla J Schramm

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P2860

Isolated limb perfusion for malignant melanoma: systematic review on effectiveness and safety

Tumor acidity, ion trapping and chemotherapeutics. I. Acid pH affects the distribution of chemotherapeutic agents in vitro

Hydrogen ion buffers for biological research

Acute metabolic alkalosis enhances response of C3H mouse mammary tumors to the weak base mitoxantrone

Drug resistance and the solid tumor microenvironment

Mechanisms of cancer drug resistance

Enhancement of chemotherapy by manipulation of tumour pH.

Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs.

Isolated limb perfusion for melanoma patients--a review of its indications and the role of tumour necrosis factor-alpha.

The European approach to in-transit melanoma lesions.

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2032-2038

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10.1021/MP200292C

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6

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Robert J Gillies

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