about
Acidic mammalian chitinase is secreted via an ADAM17/epidermal growth factor receptor-dependent pathway and stimulates chemokine production by pulmonary epithelial cellsADAM15 disintegrin is associated with aggressive prostate and breast cancer diseaseCurrent targeted therapies in the treatment of advanced colorectal cancer: a reviewA Disintegrin and Metalloprotease (ADAM): Historical Overview of Their FunctionsEGFR Signaling in Liver DiseasesG Protein-Coupled Receptor Signaling in Stem Cells and CancerEGFR Amplification and Glioblastoma Stem-Like CellsMolecular mechanisms of tissue inhibitor of metalloproteinase 2 in the tumor microenvironmentCytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10Circulating and disseminated tumor cells: diagnostic tools and therapeutic targets in motionBasic principles and emerging concepts in the redox control of transcription factorsWounding sheets of epithelial cells activates the epidermal growth factor receptor through distinct short- and long-range mechanisms.Free edges in epithelial cell sheets stimulate epidermal growth factor receptor signaling.Isolation of novel EGFR-specific VHH domains.Role of network branching in eliciting differential short-term signaling responses in the hypersensitive epidermal growth factor receptor mutants implicated in lung cancerRole of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells.Naringenin attenuates mucous hypersecretion by modulating reactive oxygen species production and inhibiting NF-κB activity via EGFR-PI3K-Akt/ERK MAPKinase signaling in human airway epithelial cells.Protein secretion in human mammary epithelial cells following HER1 receptor activation: influence of HER2 and HER3 expression.An integrated phosphoproteomics work flow reveals extensive network regulation in early lysophosphatidic acid signaling.An EGFR autocrine loop encodes a slow-reacting but dominant mode of mechanotransduction in a polarized epithelium.Stimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways.GPR30 predicts poor survival for ovarian cancerLIV-1 promotes prostate cancer epithelial-to-mesenchymal transition and metastasis through HB-EGF shedding and EGFR-mediated ERK signaling.Network analysis of epidermal growth factor signaling using integrated genomic, proteomic and phosphorylation dataGlycoprotein capture and quantitative phosphoproteomics indicate coordinated regulation of cell migration upon lysophosphatidic acid stimulation.Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt.Secreted PLA2 induces proliferation in astrocytoma through the EGF receptor: another inflammation-cancer link.Cell-signalling dynamics in time and space.Activated protein C enhances human keratinocyte barrier integrity via sequential activation of epidermal growth factor receptor and Tie2.Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17.Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells.Epidermal growth factor (EGF) ligand release by substrate-specific a disintegrin and metalloproteases (ADAMs) involves different protein kinase C (PKC) isoenzymes depending on the stimulusColon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptorMechanisms of endothelin-1-induced MAP kinase activation in adrenal glomerulosa cells.Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signalingMatrix metalloproteinase-7-catalyzed release of HB-EGF mediates deoxycholyltaurine-induced proliferation of a human colon cancer cell line.Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.Genetic or pharmacologic blockade of EGFR inhibits renal fibrosis.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
EGFR signal transactivation in cancer cells.
@ast
EGFR signal transactivation in cancer cells.
@en
type
label
EGFR signal transactivation in cancer cells.
@ast
EGFR signal transactivation in cancer cells.
@en
prefLabel
EGFR signal transactivation in cancer cells.
@ast
EGFR signal transactivation in cancer cells.
@en
P2093
P356
P1476
EGFR signal transactivation in cancer cells.
@en
P2093
P304
P356
10.1042/BST0311203
P577
2003-12-01T00:00:00Z