Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes.
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Expression of MicroRNA-146a in osteoarthritis cartilageProduction of interleukin-1 receptor antagonist by human articular chondrocytes.Cytokine networking of chondrocyte dedifferentiation in vitro and its implications for cell-based cartilage therapyGrowth abnormalities in children with type 1 diabetes, juvenile chronic arthritis, and asthmaA current review of molecular mechanisms regarding osteoarthritis and painInsights on Molecular Mechanisms of Chondrocytes Death in OsteoarthritisMechanical regulation of mitogen-activated protein kinase signaling in articular cartilageBMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1Insulin-like growth factor 1 blocks collagen release and down regulates matrix metalloproteinase-1, -3, -8, and -13 mRNA expression in bovine nasal cartilage stimulated with oncostatin M in combination with interleukin 1alphaInflammasome components ASC and AIM2 modulate the acute phase of biomaterial implant-induced foreign body responsesDistinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flowProlonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis.Immunopathogenesis of osteoarthritisMicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responsesDevelopment and retranslational validation of an in vitro model to characterize acute infections in large human joints.Abnormal human chondrocyte morphology is related to increased levels of cell-associated IL-1β and disruption to pericellular collagen type VI.Revisiting the Role of Interleukin-1 Pathway in Osteoarthritis: Interleukin-1α and -1β, and NLRP3 Inflammasome Are Not Involved in the Pathological Features of the Murine Menisectomy Model of Osteoarthritis.The inorganic pyrophosphate transporter ANK preserves the differentiated phenotype of articular chondrocyte.Muscone protects vertebral end-plate degeneration by antiinflammatory property.Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage.Dedifferentiated chondrocytes cultured in alginate beads: restoration of the differentiated phenotype and of the metabolic responses to interleukin-1beta.Expression of 92-kD type IV collagenase/gelatinase (gelatinase B) in osteoarthritic cartilage and its induction in normal human articular cartilage by interleukin 1.Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. Implications for pathogenesis.Heterogeneity in hormone responses and patterns of collagen synthesis in cloned dermal fibroblasts.Clinical significance of cytokine determination in synovial fluid.IL-1beta regulates FHL2 and other cytoskeleton-related genes in human chondrocytesFunctional genomics of osteoarthritis.A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritis.Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes.Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritisThe role of synovitis in osteoarthritis pathogenesisMonoclonal antibodies for the treatment of osteoarthritis.Generation and characterization of ABT-981, a dual variable domain immunoglobulin (DVD-Ig(TM)) molecule that specifically and potently neutralizes both IL-1α and IL-1β.miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4.Circular RNA Related to the Chondrocyte ECM Regulates MMP13 Expression by Functioning as a MiR-136 'Sponge' in Human Cartilage Degradation.RNA Interference Mediated Interleukin-1β Silencing in Inflamed Chondrocytes Decreases Target and Downstream Catabolic Responses.Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretationsModulation of Apoptosis and Differentiation by the Treatment of Sulfasalazine in Rabbit Articular Chondrocytes.MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes.Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1beta.
P2860
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P2860
Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Interleukin 1 suppresses expre ...... llagens in human chondrocytes.
@ast
Interleukin 1 suppresses expre ...... llagens in human chondrocytes.
@en
type
label
Interleukin 1 suppresses expre ...... llagens in human chondrocytes.
@ast
Interleukin 1 suppresses expre ...... llagens in human chondrocytes.
@en
prefLabel
Interleukin 1 suppresses expre ...... llagens in human chondrocytes.
@ast
Interleukin 1 suppresses expre ...... llagens in human chondrocytes.
@en
P2093
P2860
P356
P1476
Interleukin 1 suppresses expre ...... llagens in human chondrocytes.
@en
P2093
J Birkhead
L J Sandell
M B Goldring
P2860
P304
P356
10.1172/JCI113823
P407
P577
1988-12-01T00:00:00Z