Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
about
Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United StatesChemistry and structural biology of androgen receptorMetabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview.Bile Acid Metabolism and Signaling in Cholestasis, Inflammation, and CancerThe effects of microRNA on the absorption, distribution, metabolism and excretion of drugsUDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cellsCellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epitheliumDifferential allelic expression of c.1568C > A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3'UTR.Global gene expression analysis in the livers of rat offspring perinatally exposed to low doses of 2,2',4,4'-tetrabromodiphenyl ether.Potentially harmful advantage to athletes: a putative connection between UGT2B17 gene deletion polymorphism and renal disorders with prolonged use of anabolic androgenic steroids.UGT2B7 is not expressed in normal breast.New frontiers in androgen biosynthesis and metabolism.Sex differences in UDP-glucuronosyltransferase 2B17 expression and activityEvidence for geographical and racial variation in serum sex steroid levels in older men.UGT genomic diversity: beyond gene duplication.Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.A signature of balancing selection in the region upstream to the human UGT2B4 gene and implications for breast cancer risk.SNP discovery, expression and cis-regulatory variation in the UGT2B genes.Dehydroepiandrosterone, androgens and the mammary gland.Non-steroidal anti-inflammatory drugs do not influence the urinary testosterone/epitestosterone glucuronide ratio.Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspectiveBioanalytical LC-MS Method for the Quantification of Plasma Androgens and Androgen Glucuronides in Breast Cancer.Molecular pathways: Inhibiting steroid biosynthesis in prostate cancer.11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored.Phase two steroid metabolism and its roles in breast and prostate cancer patientsEvidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion.Genetic variation in androgen disposition: implications in clinical medicine including testosterone abuse.Regulation of UDP-glucuronosyltransferase 1A1 expression and activity by microRNA 491-3p.Regulation of endobiotics glucuronidation by ligand-activated transcription factors: physiological function and therapeutic potential.UGT2B gene expression analysis in multiple tobacco carcinogen-targeted tissues.The impact of genetics and hormonal contraceptives on the steroid profile in female athletes.Genetic polymorphism in metabolism and host defense enzymes: implications for human health risk assessment.Intratumoral androgen biosynthesis in prostate cancer pathogenesis and response to therapy.Nuclear receptors and endobiotics glucuronidation: the good, the bad, and the UGT.Substrate selectivity of human intestinal UDP-glucuronosyltransferases (UGTs): in silico and in vitro insights.Farnesoid X receptor alpha: a molecular link between bile acids and steroid signaling?Metabolomic profiling for the identification of novel diagnostic markers in prostate cancer.Metabolomic profiling identifies biochemical pathways associated with castration-resistant prostate cancer.Drug discovery in advanced prostate cancer: translating biology into therapy.
P2860
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P2860
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
@ast
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
@en
type
label
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
@ast
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
@en
prefLabel
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
@ast
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
@en
P2093
P1476
Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans.
@en
P2093
Alain Bélanger
Fernand Labrie
Georges Pelletier
Olivier Barbier
Sarah Chouinard
P304
P356
10.1016/J.TEM.2003.10.005
P577
2003-12-01T00:00:00Z