Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development - Wikidata - wikimedia - TriplyDB

Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

http://www.wikidata.org/entity/Q35596716

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DNA microarray data integration by ortholog gene analysis reveals potential molecular mechanisms of estrogen-dependent growth of human uterine fibroids Regulation of inflammation in cancer by eicosanoids Lipidome in colorectal cancer Epigenetic regulations of inflammatory cyclooxygenase-derived prostanoids: molecular basis and pathophysiological consequences The role of the EP receptors for prostaglandin E2 in skin and skin cancer Role of cAMP in the promotion of colorectal cancer cell growth by prostaglandin E2.An agonist sensitive, quick and simple cell-based signaling assay for determination of ligands mimicking prostaglandin E2 or E1 activity through subtype EP1 receptor: Suitable for high throughput screening Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.Prostaglandin E2-induced colonic secretion in patients with and without colorectal neoplasia The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia Potential involvement of P2Y2 receptor in diuresis of postobstructive uropathy in rats.EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway PGE₂ promotes apoptosis induced by cytokine deprivation through EP3 receptor and induces Bim in mouse mast cells.Effect of eicosapentaenoic acid on E-type prostaglandin synthesis and EP4 receptor signaling in human colorectal cancer cells.Hypertonic stress induces VEGF production in human colon cancer cell line Caco-2: inhibitory role of autocrine PGE₂ Cyclooxygenases and lipoxygenases in cancer.Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?Prostaglandin receptors EP1-4 as a potential marker for clinical outcome in urothelial bladder cancer.Oxidized low-density lipoprotein suppresses expression of prostaglandin E receptor subtype EP3 in human THP-1 macrophages Loss of EP2 receptor subtype in colonic cells compromise epithelial barrier integrity by altering claudin-4 Night eating and obesity in the EP3R-deficient mouse.EP2 and EP4 receptors on muscularis resident macrophages mediate LPS-induced intestinal dysmotility via iNOS upregulation through cAMP/ERK signals.Faecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer.Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer Effect of sphingosine kinase 1 inhibition on blood pressure.Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.Prostaglandin E2 receptor distribution and function in the gastrointestinal tract.Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells.PGE2 maintains self-renewal of human adult stem cells via EP2-mediated autocrine signaling and its production is regulated by cell-to-cell contact Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells.Transgenic insulin-like growth factor-1 stimulates activation of COX-2 signaling in mammary glands.Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.Inhibition of prostaglandin E(2) signaling through the EP(1) receptor does not affect prostacyclin production in human endothelial cells.Sesamol suppresses cyclooxygenase-2 transcriptional activity in colon cancer cells and modifies intestinal polyp development in Apc (Min/+) mice.Multifaceted roles of PGE2 in inflammation and cancer.Potential targets for colorectal cancer prevention.The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells.Retinoic acid morpholine amide (RAMA) inhibits expression of Fas ligand through EP1 receptor in colon cancer cells.The impact of inflammatory lipid mediators on colon cancer-initiating cells.

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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

http://www.wikidata.org/entity/Q35596716

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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development

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K Wakabayashi

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T Kawamori

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T Kitamura

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T Maruyama

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T Sugimura

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Y Shoji

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Y Sugimoto

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P2860

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

Structural organization of the human prostaglandin EP3 receptor subtype gene (PTGER3)

Altered eicosanoid levels in human colon cancer

Selective activation of the prostanoid EP(3) receptor reduces myocardial infarct size in rodents

Role of the prostaglandin E receptor subtype EP1 in colon carcinogenesis

Two isoforms of the EP3 receptor with different carboxyl-terminal domains. Identical ligand binding properties and different coupling properties with Gi proteins

Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase

Suppression of prostaglandin E receptor signaling by the variant form of EP1 subtype

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

Cancer epigenetics comes of age

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