Statistical epistasis is a generic feature of gene regulatory networks
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Epistasis--the essential role of gene interactions in the structure and evolution of genetic systemsComputational modeling of interactions between multiple myeloma and the bone microenvironmentGenetic and environmental factors affecting cryptic variations in gene regulatory networksGenotype-Phenotype Map Characteristics of an In silico Heart CellA framework for evolutionary systems biologyCongruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data.Genetic assimilation: a review of its potential proximate causes and evolutionary consequences.Nonlinear regulation enhances the phenotypic expression of trans-acting genetic polymorphismsBistability and oscillations in the Huang-Ferrell model of MAPK signaling.Expression profiles reveal parallel evolution of epistatic interactions involving the CRP regulon in Escherichia coli.A developmental systems perspective on epistasis: computational exploration of mutational interactions in model developmental regulatory networks.Allele interaction--single locus genetics meets regulatory biologyChromosomal loci important for cotyledon opening under UV-B in Arabidopsis thaliana.Dissecting genetic networks underlying complex phenotypes: the theoretical framework.Estimating directional epistasisHierarchical cluster-based partial least squares regression (HC-PLSR) is an efficient tool for metamodelling of nonlinear dynamic modelsGenomic analysis of QTLs and genes altering natural variation in stochastic noise.Chromatin regulators as capacitors of interspecies variations in gene expression.Parameters in dynamic models of complex traits are containers of missing heritability.Use of pleiotropy to model genetic interactions in a population.Effect of regulatory architecture on broad versus narrow sense heritability.Higher-order genetic interactions and their contribution to complex traits.Transcriptional Derepression Uncovers Cryptic Higher-Order Genetic InteractionsEpistasis between calpain 1 and its inhibitor calpastatin within breeds of cattleSurvival of the Curviest: Noise-Driven Selection for Synergistic Epistasis.Gene-Environment Interactions in Stress Response Contribute Additively to a Genotype-Environment Interaction.Why and how genetic canalization evolves in gene regulatory networksModifiers of the Genotype-Phenotype Map: Hsp90 and Beyond.Genetic variation in the Yolk protein expression network of Drosophila melanogaster: sex-biased negative correlations with longevityIndependent effects of cis- and trans-regulatory variation on gene expression in Drosophila melanogaster.Cryptic genetic variation: evolution's hidden substrateWhen parameters in dynamic models become phenotypes: a case study on flesh pigmentation in the chinook salmon (Oncorhynchus tshawytscha).Understanding quantitative genetics in the systems biology era.The fat tail of obesity as told by the genome.Genomic correlates of relationship QTL involved in fore- versus hind limb divergence in miceAdvancing genetic theory and application by metabolic quantitative trait loci analysis.Genetic regulatory network motifs constrain adaptation through curvature in the landscape of mutational (co)variance.Model Misinterpretation within Biology: Phenotypes, Statistics, Networks, and Inference.Evolutionary systems biology: what it is and why it matters.Towards systems biology of heterosis: a hypothesis about molecular network structure applied for the Arabidopsis metabolome.
P2860
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P2860
Statistical epistasis is a generic feature of gene regulatory networks
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Statistical epistasis is a generic feature of gene regulatory networks
@ast
Statistical epistasis is a generic feature of gene regulatory networks
@en
type
label
Statistical epistasis is a generic feature of gene regulatory networks
@ast
Statistical epistasis is a generic feature of gene regulatory networks
@en
prefLabel
Statistical epistasis is a generic feature of gene regulatory networks
@ast
Statistical epistasis is a generic feature of gene regulatory networks
@en
P2093
P2860
P1433
P1476
Statistical epistasis is a generic feature of gene regulatory networks
@en
P2093
Arne B Gjuvsland
Ben J Hayes
Stig W Omholt
P2860
P304
P356
10.1534/GENETICS.106.058859
P407
P577
2006-10-08T00:00:00Z