LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. - Wikidata - wikimedia - TriplyDB

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes.

LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes.

http://www.wikidata.org/entity/Q35600641

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Leukotriene B4 as a Potential Therapeutic Target for the Treatment of Metabolic Disorders Role of bile acids in carcinogenesis of pancreatic cancer: An old topic with new perspective.Leukotriene B₄ Metabolism and p70S6 Kinase 1 Inhibitors: PF-4708671 but Not LY2584702 Inhibits CYP4F3A and the ω-Oxidation of Leukotriene B₄ In Vitro and In Cellulo A Genome-Wide Association Study Uncovers a Genetic Locus Associated with Thoracic-to-Hip Ratio in Koreans Systemic leukotriene B4 receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat.Lipoxin A4 Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes.Macrophage functions in lean and obese adipose tissue.miR-378 Activates the Pyruvate-PEP Futile Cycle and Enhances Lipolysis to Ameliorate Obesity in Mice Mitochondrial fat oxidation is essential for lipid-induced inflammation in skeletal muscle in mice.Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling Myricitrin Alleviates Oxidative Stress-induced Inflammation and Apoptosis and Protects Mice against Diabetic Cardiomyopathy.Is Synovial Macrophage Activation the Inflammatory Link Between Obesity and Osteoarthritis?Regulation of inflammation by lipid mediators in oral diseases.Cross-Talk between Cancer Cells and the Tumour Microenvironment: The Role of the 5-Lipoxygenase Pathway.Adipose tissue: between the extremes.Lipidomic profiling of high-fat diet-induced obesity in mice: Importance of cytochrome P450-derived fatty acid epoxides.5-LO inhibition ameliorates palmitic acid-induced ER stress, oxidative stress and insulin resistance via AMPK activation in murine myotubes.Anti-diabetic effects and mechanisms of action of a Chinese herbal medicine preparation JQ-R in vitro and in diabetic KKAy mice.Significant association of TREM-1 with HMGB1, TLRs and RAGE in the pathogenesis of insulin resistance in obese diabetic populations.Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1.BLT2 expression improves skin integrity and protects from alterations caused by hyperglycemia in type 2 diabetes.Novel mechanism of regulation of the 5-lipoxygenase/leukotriene B4 pathway by high-density lipoprotein in macrophages.Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance.VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism.Fatty acid binding protein 4/aP2-dependent BLT1R expression and signaling.Hepatic protein tyrosine phosphatase receptor gamma links obesity-induced inflammation to insulin resistance.Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions.Arachidonic Acid Metabolite as a Novel Therapeutic Target in Breast Cancer Metastasis.Inflammatory mechanisms linking obesity and metabolic disease.Skeletal muscle inflammation and insulin resistance in obesity.Transcriptional networks of progressive diabetic peripheral neuropathy in the db/db mouse model of type 2 diabetes: An inflammatory story.Lipidomic profiling reveals soluble epoxide hydrolase as a therapeutic target of obesity-induced colonic inflammation.Inflammation and insulin resistance: New targets encourage new thinking: Galectin-3 and LTB4 are pro-inflammatory molecules that can be targeted to restore insulin sensitivity.Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models

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LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes.

http://www.wikidata.org/entity/Q35600641

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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LTB4 promotes insulin resistan ...... ges, hepatocytes and myocytes.

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Nature Medicine

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Andrew Johnson

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Da Young Oh

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Gautam Bandyopadhyay

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Heekyung Chung

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Jachelle M Ofrecio

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Michael Maris

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Min Lu

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Saswata Talukdar

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Sayaka Taguchi

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William S Lagakos

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

Lipidomics reveals a remarkable diversity of lipids in human plasma

Obesity is associated with macrophage accumulation in adipose tissue

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance

BLT1 and BLT2: the leukotriene B(4) receptors

Hydroxyeicosanoids bind to and activate the low affinity leukotriene B4 receptor, BLT2

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21

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Jerrold M. Olefsky

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2015-02-23T00:00:00Z

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272683183

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25706874

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