Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
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The Regulatory Role of KIBRA and PTPN14 in Hippo Signaling and BeyondA Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue SarcomasFOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathwaysTargeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer TherapyFormation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer ModelSOX2 is required to maintain cancer stem cells in ovarian cancer.Target Therapies for Uterine Carcinosarcomas: Current Evidence and Future Perspectives.YAP promotes tumorigenesis and cisplatin resistance in neuroblastomaACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer.The Notch pathway promotes the cancer stem cell characteristics of CD90+ cells in hepatocellular carcinomaA feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells.PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity.Prognostic value of the Hippo pathway transcriptional coactivators YAP/TAZ and β1-integrin in conventional osteosarcoma.A directly negative interaction of miR-203 and ZEB2 modulates tumor stemness and chemotherapy resistance in nasopharyngeal carcinoma.Overexpression of Transforming Acidic Coiled Coil‑Containing Protein 3 Reflects Malignant Characteristics and Poor Prognosis of Glioma.RASAL2, a RAS GTPase-activating protein, inhibits stemness and epithelial-mesenchymal transition via MAPK/SOX2 pathway in bladder cancer.Osteosarcoma Stem Cells Have Active Wnt/β-catenin and Overexpress SOX2 and KLF4.YAP/TAZ at the Roots of Cancer.Adipocytes properties and crosstalk with immune system in obesity-related inflammation.Intra-tumor heterogeneity from a cancer stem cell perspective.GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth.YAP and the Hippo pathway in pediatric cancer.Chemoresistance of Lung and Breast Cancer Cells Growing Under Prolonged Periods of Serum Starvation.Expression Analysis of the Hippo Cascade Indicates a Role in Pituitary Stem Cell Development.Regulation of human glioma cell apoptosis and invasion by miR-152-3p through targeting DNMT1 and regulating NF2 : MiR-152-3p regulate glioma cell apoptosis and invasion.New variant and expression studies provide further insight into the genotype-phenotype correlation in YAP1-related developmental eye disorders.Breast Cancer Spheroids Reveal a Differential Cancer Stem Cell Response to Chemotherapeutic Treatment.The long noncoding RNA HOTAIR activates the Hippo pathway by directly binding to SAV1 in renal cell carcinoma.Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells.Myeloid Zinc Finger 1 and GA Binding Protein Co-operate with Sox2 in Regulating the Expression of Yes-Associated Protein 1 in Cancer Cells.Cancer Cell Plasticity: Rapid Reversal of Chemosensitivity and Expression of Stemness Markers in Lung and Breast Cancer Tumorspheres.Small-sized colorectal cancer cells harbor metastatic tumor-initiating cells.MiR-638 acts as a tumor suppressor gene in gastric cancer.Synaptopodin-2 suppresses metastasis of triple-negative breast cancer via inhibition of YAP/TAZ activity.WWC1 promotes podocyte survival via stabilizing slit diaphragm protein dendrin.WWC3 regulates the Wnt and Hippo pathways via Dishevelled proteins and large tumour suppressor 1, to suppress lung cancer invasion and metastasis.GPR133 Promotes Glioblastoma Growth in Hypoxia.Upregulation of SOX2-activated lncRNA ANRIL promotes nasopharyngeal carcinoma cell growth.The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization.
P2860
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P2860
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
@ast
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
@en
type
label
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
@ast
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
@en
prefLabel
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
@ast
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
@en
P2093
P2860
P356
P1476
Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells
@en
P2093
Claudio Basilico
Eugenia Han
Kirk Rattanakorn
N Sumru Bayin
Upal Basu-Roy
P2860
P2888
P356
10.1038/NCOMMS7411
P407
P577
2015-04-02T00:00:00Z