MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-κB p65 and binding to cytokine promoters: importance of extracellular domain.
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The MUC1 extracellular domain subunit is found in nuclear speckles and associates with spliceosomesIntra- and Extra-Cellular Events Related to Altered Glycosylation of MUC1 Promote Chronic Inflammation, Tumor Progression, Invasion, and MetastasisMucin-1 Increases Renal TRPV5 Activity In Vitro, and Urinary Level Associates with Calcium Nephrolithiasis in PatientsMUC1: a multifaceted oncoprotein with a key role in cancer progression.Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling.Complex of MUC1, CIN85 and Cbl in Colon Cancer Progression and Metastasis.Mucin1 shifts Smad3 signaling from the tumor-suppressive pSmad3C/p21(WAF1) pathway to the oncogenic pSmad3L/c-Myc pathway by activating JNK in human hepatocellular carcinoma cells.Emerging potential of natural products for targeting mucins for therapy against inflammation and cancer.Binding of Galectin-3, a β-Galactoside-binding Lectin, to MUC1 Protein Enhances Phosphorylation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) and Akt, Promoting Tumor Cell MalignancyGenetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations.Hepatitis C virus NS5A promotes insulin resistance through IRS-1 serine phosphorylation and increased gluconeogenesis.Host response in tumor diagnosis and prognosis: importance of immunologists and pathologists allianceProteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness.Mammalian adenylyl cyclase-associated protein 1 (CAP1) regulates cofilin function, the actin cytoskeleton, and cell adhesion.Altered glycosylation of MUC1 influences its association with CIN85: the role of this novel complex in cancer cell invasion and migration.Molecular characterization of antigen-peptide pulsed dendritic cells: immature dendritic cells develop a distinct molecular profile when pulsed with antigen peptideChromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1.MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway.MUC1 immunotherapy is here to stay.Mechanisms of antitumor and immune-enhancing activities of MUC1/sec, a secreted form of mucin-1.Basics and recent advances of two dimensional- polyacrylamide gel electrophoresis.Genetic variants of mucins: unexplored conundrum.Reduced expression of the chromatin remodeling gene ARID1A enhances gastric cancer cell migration and invasion via downregulation of E-cadherin transcription.PPARγ E3 ubiquitin ligase regulates MUC1-C oncoprotein stability.Transmembrane Mucins: Signaling Receptors at the Intersection of Inflammation and Cancer.Prevention of colitis-associated colon cancer using a vaccine to target abnormal expression of the MUC1 tumor antigen.Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer.14-3-3z sequesters cytosolic T-bet, upregulating IL-13 levels in TC2 and CD8+ lymphocytes from patients with scleroderma.Transmembrane protein 170B is a novel breast tumorigenesis suppressor gene that inhibits the Wnt/β-catenin pathway.Synergistic Anticancer Effect of Peptide-Docetaxel Nanoassembly Targeted to Tubulin: Toward Development of Dual Warhead Containing Nanomedicine.Development and application of a double- antibody sandwich ELISA kit for the detection of serum MUC1 in lung cancer patients.Peroxisome Proliferator-Activated Receptor γ and PGC-1α in Cancer: Dual Actions as Tumor Promoter and Suppressor.
P2860
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P2860
MUC1 protein expression in tumor cells regulates transcription of proinflammatory cytokines by forming a complex with nuclear factor-κB p65 and binding to cytokine promoters: importance of extracellular domain.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
MUC1 protein expression in tum ...... tance of extracellular domain.
@ast
MUC1 protein expression in tum ...... tance of extracellular domain.
@en
type
label
MUC1 protein expression in tum ...... tance of extracellular domain.
@ast
MUC1 protein expression in tum ...... tance of extracellular domain.
@en
prefLabel
MUC1 protein expression in tum ...... tance of extracellular domain.
@ast
MUC1 protein expression in tum ...... tance of extracellular domain.
@en
P2860
P356
P1476
MUC1 protein expression in tum ...... tance of extracellular domain.
@en
P2093
Lixin Zhang
Olivera J Finn
P2860
P304
42248-42256
P356
10.1074/JBC.M111.297630
P407
P577
2011-10-22T00:00:00Z