The PDL1-PD1 axis converts human TH1 cells into regulatory T cells. - Wikidata - wikimedia - TriplyDB

The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

http://www.wikidata.org/entity/Q35607698

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TCR-Engineered T Cells Meet New Challenges to Treat Solid Tumors: Choice of Antigen, T Cell Fitness, and Sensitization of Tumor Milieu Disrupted regulatory T cell homeostasis in inflammatory bowel diseases Localization and upregulation of survivin in cancer health disparities: a clinical perspective Immunological cells and functions in Gaucher disease Role of the PD-1 pathway in the immune response The programmed death-1 immune-suppressive pathway: barrier to antitumor immunity Molecular mechanisms of T cell co-stimulation and co-inhibition Transcriptional profiling of the circulating immune response to lassa virus in an aerosol model of exposure Phenotypic T cell exhaustion in a murine model of bacterial infection in the setting of pre-existing malignancy Acute graft-versus-host disease: a bench-to-bedside update.PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses Rapamycin resistant murine th9 cells have a stable in vivo phenotype and inhibit graft-versus-host reactivity.Soluble Programmed Death 1 (PD-1) Is Decreased in Patients With Immune Thrombocytopenia (ITP): Potential Involvement of PD-1 Pathway in ITP Immunopathogenesis.Expansion of CD25-Negative Forkhead Box P3-Positive T Cells during HIV and Mycobacterium tuberculosis Infection CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells.TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression.TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cells Immune evasion strategies used by Helicobacter pylori.Recent Insight into the Role of the PD-1/PD-L1 Pathway in Feto-Maternal Tolerance and Pregnancy.PD-1, PD-L1 (B7-H1) and Tumor-Site Immune Modulation Therapy: The Historical Perspective.Programmed cell death receptor ligand 1 modulates the regulatory T cells' capacity to repress shock/sepsis-induced indirect acute lung injury by recruiting phosphatase SRC homology region 2 domain-containing phosphatase 1.B7H1/CD80 interaction augments PD-1-dependent T cell apoptosis and ameliorates graft-versus-host disease CD4 T Cells Mediate Both Positive and Negative Regulation of the Immune Response to HIV Infection: Complex Role of T Follicular Helper Cells and Regulatory T Cells in Pathogenesis Retinoic acid imprints a mucosal-like phenotype on dendritic cells with an increased ability to fuel HIV-1 infection.Combination of alphavirus replicon particle-based vaccination with immunomodulatory antibodies: therapeutic activity in the B16 melanoma mouse model and immune correlates.Viral infection of human lung macrophages increases PDL1 expression via IFNβ.PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer PDL1 expression is an independent prognostic factor in localized GIST.Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity.Recent developments on immunotherapy for brain cancer.Regulation of Gag- and Env-Specific CD8+ T Cell Responses in ART-Naïve HIV-Infected Patients: Potential Implications for Individualized Immunotherapy.Anti-PD-1/PD-L1 therapy of human cancer: past, present, and future.Anti-IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function.Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression.Nivolumab-associated acute glomerulonephritis: a case report and literature review.The dynamic lives of T cells: new approaches and themes Programmed death-1 checkpoint blockade in acute myeloid leukemia.Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E2-induced regulatory T cell expansion.Mesenchymal stromal cells: heroes or non-combatants?Harnessing autophagy for cell fate control gene therapy

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The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

http://www.wikidata.org/entity/Q35607698

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name

The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

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The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

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The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

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The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

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prefLabel

The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

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The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

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SCITRANSLMED.3003130

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Science Translational Medicine

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The PDL1-PD1 axis converts human TH1 cells into regulatory T cells.

@en

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Alice He

http://www.w3.org/2001/XMLSchema#string

Bruce L Levine

http://www.w3.org/2001/XMLSchema#string

Carl H June

http://www.w3.org/2001/XMLSchema#string

Courtney W Mangus

http://www.w3.org/2001/XMLSchema#string

Daniel H Fowler

http://www.w3.org/2001/XMLSchema#string

Fang Wei

http://www.w3.org/2001/XMLSchema#string

James C M Wang

http://www.w3.org/2001/XMLSchema#string

James L Riley

http://www.w3.org/2001/XMLSchema#string

Jason E Foley

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Medin

http://www.w3.org/2001/XMLSchema#string

P2860

The PD-1 pathway in tolerance and autoimmunity

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

Human T regulatory cell therapy: take a billion or so and call me in the morning

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer

Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism

Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1

Molecular antagonism and plasticity of regulatory and inflammatory T cell programs

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

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10.1126/SCITRANSLMED.3003130

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22133721

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3235958

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