Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
about
SXR, a novel steroid and xenobiotic-sensing nuclear receptorPossible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalaciaGrapefruit juice-drug interactionsRoles of rifampicin in drug-drug interactions: underlying molecular mechanisms involving the nuclear pregnane X receptor.Pharmacokinetic Interaction of Rifampicin with Oral Versus Intravenous Anticancer Drugs: Challenges, Dilemmas and Paradoxical Effects Due to Multiple MechanismsEfficacy, Pharmacokinetics, and Metabolism of Tetrahydroquinoline Inhibitors of Plasmodium falciparum Protein FarnesyltransferaseRenal drug transporters and their significance in drug-drug interactionsInsights into CYP2B6-mediated drug-drug interactionsExposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juiceFunctionally defective or altered CYP3A4 and CYP3A5 single nucleotide polymorphisms and their detection with genotyping testsEffect of itraconazole on the pharmacokinetics of prednisolone and methylprednisolone and cortisol secretion in healthy subjectsEnvironmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response elementAetiology of pulmonary symptoms in HIV-infected smear negative recurrent PTB suspects in Kampala, Uganda: a cross-sectional studyGenetic variability in CYP3A5 and its possible consequences.Pharmacokinetic interaction between ritonavir and indinavir in healthy volunteersPharmacokinetic Interaction between amprenavir and rifabutin or rifampin in healthy malesMacrolide - induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycinThe drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.The human CYP3A subfamily: practical considerations.P-Glycoprotein- and cytochrome P-450-mediated herbal drug interactions.An investigation of the interaction between halofantrine, CYP2D6 and CYP3A4: studies with human liver microsomes and heterologous enzyme expression systemsThe role of CYP3A4 in the biotransformation of bile acids and therapeutic implication for cholestasis.Strategies to overcome simultaneous P-glycoprotein mediated efflux and CYP3A4 mediated metabolism of drugs.Zonisamide in pediatric epilepsy: review of the Japanese experience.Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes.CYP2B6: new insights into a historically overlooked cytochrome P450 isozymeEfflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals.Primary porcine enterocyte and hepatocyte cultures to study drug oxidation reactionsFood-drug interaction: grapefruit juice augments drug bioavailability--mechanism, extent and relevance.CYP3A4-mediated lopinavir bioactivation and its inhibition by ritonavir.Gut wall metabolism of verapamil in older people: effects of rifampicin-mediated enzyme inductionConcentrations and effects of buspirone are considerably reduced by rifampicinEffect of rifampicin on pravastatin pharmacokinetics in healthy subjects.The effect of quinidine, used as a probe for the involvement of P-glycoprotein, on the intestinal absorption and pharmacodynamics of methadone.A new CYP3A5 variant, CYP3A5*11, is shown to be defective in nifedipine metabolism in a recombinant cDNA expression system.Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.Human immunodeficiency virus and leprosy coinfection: challenges in resource-limited setupsIntravenous diltiazem and CYP3A-mediated metabolism.Pharmacokinetic variability of anticancer agents.
P2860
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P2860
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
@ast
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
@en
type
label
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
@ast
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
@en
prefLabel
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
@ast
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
@en
P2093
P2860
P356
P1476
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
@en
P2093
J C Kolars
J D Schuetz
P B Watkins
P Schmiedlin-Ren
P2860
P304
P356
10.1172/JCI116064
P407
P577
1992-11-01T00:00:00Z