The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation.
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The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's diseaseNeuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunityThe gut-brain axis: is intestinal inflammation a silent driver of Parkinson's disease pathogenesis?Chondrocyte-specific pathology during skeletal growth and therapeutics in a murine model of pseudoachondroplasiaViral pre-challenge increases central nervous system inflammation after intracranial interleukin-1β injection.A spirulina-enhanced diet provides neuroprotection in an α-synuclein model of Parkinson's disease.Regulation of microglia activity by glaucocalyxin-A: attenuation of lipopolysaccharide-stimulated neuroinflammation through NF-κB and p38 MAPK signaling pathwaysPreconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C).Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease.Inhibition of Calpain Activation Protects MPTP-Induced Nigral and Spinal Cord Neurodegeneration, Reduces Inflammation, and Improves Gait Dynamics in Mice.Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T MutantAltered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases.Associations of Matrix Metalloproteinase-9 and Tissue Inhibitory Factor-1 Polymorphisms With Parkinson Disease in Taiwan.A novel synthetic compound MCAP suppresses LPS-induced murine microglial activation in vitro via inhibiting NF-kB and p38 MAPK pathways.Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice.Parkinson's disease and enhanced inflammatory response.Induction of CNS α-synuclein pathology by fibrillar and non-amyloidogenic recombinant α-synucleinMicroglia and neurodegeneration: the role of systemic inflammation.Alpha-synuclein: from secretion to dysfunction and death.The role of innate and adaptive immunity in Parkinson's disease.Protein Transmission, Seeding and Degradation: Key Steps for α-Synuclein Prion-Like PropagationThe prion hypothesis of Parkinson's disease.Transcriptional control of microglia phenotypes in health and disease.Lumbee traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms.Oligomeropathies and pathogenesis of Alzheimer and Parkinson's diseases.Role of the JAK/STAT signaling pathway in regulation of innate immunity in neuroinflammatory diseases.LRRK2 and the Immune System.Parkinson's disease: Microglial/macrophage-induced immunoexcitotoxicity as a central mechanism of neurodegenerationα-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology.Immune responses in Parkinson's disease: interplay between central and peripheral immune systems.Rotenone could activate microglia through NFκB associated pathway.Mitochondrial Respiration in Intact Peripheral Blood Mononuclear Cells and Sirtuin 3 Activity in Patients with Movement Disorders.Creation of a gated antibody as a conditionally functional synthetic protein.Updates on immunity and inflammation in Parkinson disease pathology.Let's make microglia great again in neurodegenerative disorders.Rhinacanthin C Alleviates Amyloid-β Fibrils' Toxicity on Neurons and Attenuates Neuroinflammation Triggered by LPS, Amyloid-β, and Interferon-γ in Glial Cells.Microbes Tickling Your Tummy: the Importance of the Gut-Brain Axis in Parkinson's Disease.Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways.Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production.
P2860
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P2860
The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The acute inflammatory respons ...... ed by peripheral inflammation.
@ast
The acute inflammatory respons ...... ed by peripheral inflammation.
@en
type
label
The acute inflammatory respons ...... ed by peripheral inflammation.
@ast
The acute inflammatory respons ...... ed by peripheral inflammation.
@en
prefLabel
The acute inflammatory respons ...... ed by peripheral inflammation.
@ast
The acute inflammatory respons ...... ed by peripheral inflammation.
@en
P2860
P50
P356
P1476
The acute inflammatory respons ...... ted by peripheral inflammation
@en
P2093
Nicola R Sibson
Yvonne Couch
P2860
P2888
P356
10.1186/1742-2094-8-166
P577
2011-11-28T00:00:00Z
P5875
P6179
1023291055