Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.
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Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implicationsRegulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signalingTrop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions.Correlation between Trop2 and amphiregulin coexpression and overall survival in gastric cancerLoss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC.TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma.Trop2 is overexpressed in gastric cancer and predicts poor prognosis.Loss of TACSTD2 contributed to squamous cell carcinoma progression through attenuating TAp63-dependent apoptosis.Trop2: from development to disease.Tumor-associated calcium signal transducer 2 regulates neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway.A surprising cross-species conservation in the genomic landscape of mouse and human oral cancer identifies a transcriptional signature predicting metastatic disease.Prognostic role and clinical significance of trophoblast cell surface antigen 2 in various carcinomas.Anti-Trop2 blockade enhances the therapeutic efficacy of ErbB3 inhibition in head and neck squamous cell carcinoma.Trop2 regulates motility and lamellipodia formation in cultured fetal lung fibroblasts.The emergence of trophoblast cell-surface antigen 2 (TROP-2) as a novel cancer target.
P2860
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P2860
Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
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2011年论文
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name
Loss of Trop2 promotes carcino ...... on in squamous cell carcinoma.
@ast
Loss of Trop2 promotes carcino ...... on in squamous cell carcinoma.
@en
type
label
Loss of Trop2 promotes carcino ...... on in squamous cell carcinoma.
@ast
Loss of Trop2 promotes carcino ...... on in squamous cell carcinoma.
@en
prefLabel
Loss of Trop2 promotes carcino ...... on in squamous cell carcinoma.
@ast
Loss of Trop2 promotes carcino ...... on in squamous cell carcinoma.
@en
P2093
P2860
P1476
Loss of Trop2 promotes carcino ...... on in squamous cell carcinoma.
@en
P2093
Christine H Chung
Dorota Grabowska
James Lewis
Jason D Weber
Jeffrey M Arbeit
Jianbo Wang
Kaihua Zhang
Loren S Michel
Peter Humphrey
P2860
P304
P356
10.1158/1541-7786.MCR-11-0241
P577
2011-10-04T00:00:00Z