Status of the intracellular gate in the activated-not-open state of shaker K+ channels
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Mechanosensitive gating of Kv channelsA quantitative description of KcsA gating I: macroscopic currentsUse of voltage clamp fluorimetry in understanding potassium channel gating: a review of Shaker fluorescence data.The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers.The electrically silent Kv6.4 subunit confers hyperpolarized gating charge movement in Kv2.1/Kv6.4 heterotetrameric channels.Position and motions of the S4 helix during opening of the Shaker potassium channel.Tarantula toxins interacting with voltage sensors in potassium channels.Elucidating the molecular basis of action of a classic drug: guanidine compounds as inhibitors of voltage-gated potassium channels.Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensorsCoupling between the voltage-sensing and pore domains in a voltage-gated potassium channel.Coupling of voltage-sensors to the channel pore: a comparative viewMembrane stretch slows the concerted step prior to opening in a Kv channelAn S6 mutation in BK channels reveals beta1 subunit effects on intrinsic and voltage-dependent gatingTetrameric assembly of KvLm K+ channels with defined numbers of voltage sensors.Structure and anticipatory movements of the S6 gate in Kv channelsOpening the shaker K+ channel with hanatoxin.The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state.Stabilization of the conductive conformation of a voltage-gated K+ (Kv) channel: the lid mechanismhERG gating microdomains defined by S6 mutagenesis and molecular modeling.Slow inactivation in Shaker K channels is delayed by intracellular tetraethylammonium.K+ channel modulators for the treatment of neurological disorders and autoimmune diseasesThe isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel.Mutations in the S6 gate isolate a late step in the activation pathway and reduce 4-AP sensitivity in shaker K(v) channel.Being flexible: the voltage-controllable activation gate of kv channels.Potassium channels: structures, diseases, and modulators.Mechanisms of activation of voltage-gated potassium channels.Basis for allosteric open-state stabilization of voltage-gated potassium channels by intracellular cations.Effective pore size and radius of capture for K(+) ions in K-channels.An intersubunit interaction between S4-S5 linker and S6 is responsible for the slow off-gating component in Shaker K+ channels.Voltage clamp fluorimetry reveals a novel outer pore instability in a mammalian voltage-gated potassium channel.Pore size matters for potassium channel conductance.Dual stretch responses of mHCN2 pacemaker channels: accelerated activation, accelerated deactivation.Closed-channel block of BK potassium channels by bbTBA requires partial activation.Coupling of S4 helix translocation and S6 gating analyzed by molecular-dynamics simulations of mutated Kv channels.Activation gating of hERG potassium channels: S6 glycines are not required as gating hinges.Neutralisation of a single voltage sensor affects gating determinants in all four pore-forming S6 segments of Ca(V)1.2: a cooperative gating model.
P2860
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P2860
Status of the intracellular gate in the activated-not-open state of shaker K+ channels
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Status of the intracellular gate in the activated-not-open state of shaker K+ channels
@ast
Status of the intracellular gate in the activated-not-open state of shaker K+ channels
@en
type
label
Status of the intracellular gate in the activated-not-open state of shaker K+ channels
@ast
Status of the intracellular gate in the activated-not-open state of shaker K+ channels
@en
prefLabel
Status of the intracellular gate in the activated-not-open state of shaker K+ channels
@ast
Status of the intracellular gate in the activated-not-open state of shaker K+ channels
@en
P2860
P356
P1476
Status of the intracellular gate in the activated-not-open state of shaker K+ channels
@en
P2093
Donato del Camino
Max Kanevsky
P2860
P304
P356
10.1085/JGP.200509385
P50
P577
2005-11-01T00:00:00Z