Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes. - Wikidata - wikimedia - TriplyDB

Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.

Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.

http://www.wikidata.org/entity/Q35631762

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Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential Bile Acid Metabolism and Signaling in Cholestasis, Inflammation, and Cancer Bile acids are nutrient signaling hormones Bile acid metabolism and signaling Bile acid signaling in metabolic disease and drug therapy Conjugated bile acid-activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression Developmental origins of NAFLD: a womb with a clue.Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats.Bile Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Promotes Neuroinflammation during Hepatic Encephalopathy in Mice.Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2.Bile acids and the gut microbiome.INTRACELLULAR SIGNALING BY BILE ACIDS.Bile acid signaling in lipid metabolism: metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice.Sphingosine-1-phosphate receptor 2 Intestinal transport and metabolism of bile acids A novel comparative pattern count analysis reveals a chronic ethanol-induced dynamic shift in immediate early NF-κB genome-wide promoter binding during liver regeneration.Consequences of bile salt biotransformations by intestinal bacteria.Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells.Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism.Preference of Conjugated Bile Acids over Unconjugated Bile Acids as Substrates for OATP1B1 and OATP1B3.Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma.FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of β-Klotho.Pleiotropic roles of bile acids in metabolism.Therapeutic targets for cholestatic liver injury Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro.The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases.Effects of bile acids on neurological function and disease.Decoding the vasoregulatory activities of bile acid-activated receptors in systemic and portal circulation: role of gaseous mediators.New therapeutic concepts in bile acid transport and signaling for management of cholestasis.Bile acids and cardiovascular function in cirrhosis.The role of bile acids in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.Murine model of long-term obstructive jaundice.Sphingosine-1-phosphate/S1P receptors signaling modulates cell migration in human bone marrow-derived mesenchymal stem cells.Cholesterol attenuates cytoprotective effects of phosphatidylcholine against bile salts.Role of AMP-activated protein kinase α1 in 17α-ethinylestradiol-induced cholestasis in rats.

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P2860

Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.

http://www.wikidata.org/entity/Q35631762

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Conjugated bile acids activate ...... in primary rodent hepatocytes.

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Elaine Studer

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Huiping Zhou

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Kazuaki Takabe

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Luyong Zhang

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Masayuki Nagahashi

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Pat Bohdan

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Phillip B Hylemon

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Renping Zhao

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Ruihua Shi

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Weiren Xu

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P2860

Identification of membrane-type receptor for bile acids (M-BAR)

A G protein-coupled receptor responsive to bile acids

Bile acids: regulation of apoptosis by ursodeoxycholic acid

The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.

Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2.

Structural features of EDG1 receptor-ligand complexes revealed by computational modeling and mutagenesis.

Bile acids regulate hepatic gluconeogenic genes and farnesoid X receptor via G(alpha)i-protein-coupled receptors and the AKT pathway.

Extracellular and intracellular actions of sphingosine-1-phosphate

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267-276

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10.1002/HEP.24681

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1

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55

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51656407

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21932398

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3245352

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