Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression
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A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virusExpression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiationSTAT6 and STAT1 Pathway Activation in Circulating Lymphocytes and Monocytes as Predictor of Treatment Response in Rheumatoid ArthritisPim serine/threonine kinases regulate the stability of Socs-1 proteinResolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation.Interleukin-4 induction of the CC chemokine TARC (CCL17) in murine macrophages is mediated by multiple STAT6 sites in the TARC gene promoter.A dynamic network of transcription in LPS-treated human subjects.Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis.Dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitroInduction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13.Effects of prolactin on signal transduction and gene expression: possible relevance for systemic lupus erythematosus.The impact of polymorphisms in STAT6 on treatment outcome in HCV infected Taiwanese ChineseInduction of interferon-stimulated genes on the IL-4 response axis by Epstein-Barr virus infected human b cells; relevance to cellular transformation.Regulation of cytokine receptor signaling by SOCS1.Type I interferons and their therapeutic role in Th2-regulated inflammatory disorders.The Interleukin-13 Receptor-α1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but Not IL-4.Interferons as pathogenic effectors in autoimmunity.Suppression of inflammation in ulcerative colitis by interferon-β-1a is accompanied by inhibition of IL-13 production.Interferon gamma stabilizes the T helper cell type 1 phenotype.The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease.Transient inhibition of interleukin 4 signaling by T cell receptor ligation.Interferon-lambda (IFN-λ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes.SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function.p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity.Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain.Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases.T-bet knockout prevents Helicobacter felis-induced gastric cancer.Type I interferons in regulation of mucosal immunity.Type I IFN-mediated regulation of IL-1 production in inflammatory disorders.IL-17A enhances IL-13 activity by enhancing IL-13-induced signal transducer and activator of transcription 6 activation.Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264.The Protective Role of Type I Interferons in the Gastrointestinal Tract.Counter-regulation mechanism of IL-4 and IFN-α signal transduction through cytosolic retention of the pY-STAT6:pY-STAT2:p48 complex.Respiratory syncytial virus infection induces a subset of types I and III interferons in human dendritic cells.Stat6-Dependent Inhibition of Mincle Expression in Mouse and Human Antigen-Presenting Cells by the Th2 Cytokine IL-4Gamma interferon-induced nitric oxide production in mouse CD5+ B1-like cell line and its association with apoptotic cell death.IFNβ autocrine feedback is required to sustain TLR induced production of MCP-1 in macrophages.Regulation of Fc epsilonRI expression on human monocytic cells by ligand and IL-4.Deactivation of STAT6 through serine 707 phosphorylation by JNK.
P2860
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P2860
Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Interferons inhibit activation ...... nducing SOCS-1 gene expression
@ast
Interferons inhibit activation ...... nducing SOCS-1 gene expression
@en
type
label
Interferons inhibit activation ...... nducing SOCS-1 gene expression
@ast
Interferons inhibit activation ...... nducing SOCS-1 gene expression
@en
prefLabel
Interferons inhibit activation ...... nducing SOCS-1 gene expression
@ast
Interferons inhibit activation ...... nducing SOCS-1 gene expression
@en
P2093
P2860
P356
P1476
Interferons inhibit activation ...... nducing SOCS-1 gene expression
@en
P2093
C Venkataraman
H L Dickensheets
U Schindler
P2860
P304
10800-10805
P356
10.1073/PNAS.96.19.10800
P407
P577
1999-09-01T00:00:00Z