Axonal degeneration is mediated by the mitochondrial permeability transition pore. - Wikidata - wikimedia - TriplyDB

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

http://www.wikidata.org/entity/Q35633387

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MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling Traumatic Axonal Injury: Mechanisms and Translational Opportunities Neuronal endoplasmic reticulum stress in axon injury and neurodegeneration Emerging roles of extracellular vesicles in the nervous system Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration Quantification of mitochondrial morphology in neurites of dopaminergic neurons using multiple parameters Wld(S) reduces paraquat-induced cytotoxicity via SIRT1 in non-neuronal cells by attenuating the depletion of NAD A HuD-ZBP1 ribonucleoprotein complex localizes GAP-43 mRNA into axons through its 3' untranslated region AU-rich regulatory element.Axon degeneration: Molecular mechanisms of a self-destruction pathway Atomic force microscopy reveals important differences in axonal resistance to injury.A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity.Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicity A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons Calcium-dependent proteasome activation is required for axonal neurofilament degradation A BAX/BAK and cyclophilin D-independent intrinsic apoptosis pathway Diapause formation and downregulation of insulin-like signaling via DAF-16/FOXO delays axonal degeneration and neuronal loss.Preserve and protect: maintaining axons within functional circuits.GNX-4728, a novel small molecule drug inhibitor of mitochondrial permeability transition, is therapeutic in a mouse model of amyotrophic lateral sclerosis.WldS and PGC-1α regulate mitochondrial transport and oxidation state after axonal injury Axons degenerate in the absence of mitochondria in C. elegans Activity-dependent degeneration of axotomized neuromuscular synapses in Wld S mice.Human coronavirus-induced neuronal programmed cell death is cyclophilin d dependent and potentially caspase dispensable.A conditioning lesion protects axons from degeneration via the Wallenda/DLK MAP kinase signaling cascade Ketone bodies mediate antiseizure effects through mitochondrial permeability transition.Live Imaging of Calcium Dynamics during Axon Degeneration Reveals Two Functionally Distinct Phases of Calcium Influx.WldS but not Nmnat1 protects dopaminergic neurites from MPP+ neurotoxicity.Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP.Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy.Axon degeneration in Parkinson's disease Mitochondria and Caspases Tune Nmnat-Mediated Stabilization to Promote Axon Regeneration Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons.Axonal Degeneration in Retinal Ganglion Cells Is Associated with a Membrane Polarity-Sensitive Redox Process.Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy SCG10 is a JNK target in the axonal degeneration pathway.Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons.Sod1 gene ablation in adult mice leads to physiological changes at the neuromuscular junction similar to changes that occur in old wild-type mice.Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury

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Axonal degeneration is mediated by the mitochondrial permeability transition pore.

http://www.wikidata.org/entity/Q35633387

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

@ast

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

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type

label

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

@ast

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

@en

prefLabel

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

@ast

Axonal degeneration is mediated by the mitochondrial permeability transition pore.

@en

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JNEUROSCI.4065-10.2011

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Journal of Neuroscience

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Axonal degeneration is mediated by the mitochondrial permeability transition pore

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P2093

Claudio Hetz

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Felipe A Court

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Jaime Alvarez

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Jeffery L Twiss

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Juan S Jara

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Sebastian Zamorano

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Soonmoon Yoo

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P2860

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

A local mechanism mediates NAD-dependent protection of axon degeneration

The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Translational control of ribosomal protein L4 mRNA is required for rapid neurite regeneration

Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons

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10.1523/JNEUROSCI.4065-10.2011

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3

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31

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Sebastian A Barrientos

Nicolas W Martinez

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2011-01-01T00:00:00Z

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21248121

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3245862

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