Mechanisms mediating androgen receptor reactivation after castration.
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Androgen receptor variants occur frequently in castration resistant prostate cancer metastasesAdaptive responses of androgen receptor signaling in castration-resistant prostate cancerMedical strategies for treatment of castration resistant prostate cancer (CRPC) docetaxel resistantAbiraterone in the treatment of metastatic castration-resistant prostate cancerPeptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancerEffect of small molecules modulating androgen receptor (SARMs) in human prostate cancer modelsDifferential effects of genistein on prostate cancer cells depend on mutational status of the androgen receptorAR variant ARv567es induces carcinogenesis in a novel transgenic mouse model of prostate cancer.TACC2 is an androgen-responsive cell cycle regulator promoting androgen-mediated and castration-resistant growth of prostate cancerEnhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activationThe Activity of SN33638, an Inhibitor of AKR1C3, on Testosterone and 17β-Estradiol Production and Function in Castration-Resistant Prostate Cancer and ER-Positive Breast Cancer.Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancerNeuropilin-1 is upregulated in the adaptive response of prostate tumors to androgen-targeted therapies and is prognostic of metastatic progression and patient mortality.Targeting poly(ADP-ribose) polymerase and the c-Myb-regulated DNA damage response pathway in castration-resistant prostate cancer.New frontiers in androgen biosynthesis and metabolism.Developments in nonsteroidal antiandrogens targeting the androgen receptor.Decreased expression and androgen regulation of the tumor suppressor gene INPP4B in prostate cancer.Dose-dependent effects of small-molecule antagonists on the genomic landscape of androgen receptor binding.Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies.Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cells.Characterization of tumor differentiation factor (TDF) and its receptor (TDF-R).PTEN genomic deletion predicts prostate cancer recurrence and is associated with low AR expression and transcriptional activity.Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse modelAndrogen receptor promotes gastric cancer cell migration and invasion via AKT-phosphorylation dependent upregulation of matrix metalloproteinase 9Melanoma antigen gene protein-A11 (MAGE-11) F-box links the androgen receptor NH2-terminal transactivation domain to p160 coactivators.Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer.The antiandrogenic effect of finasteride against a mutant androgen receptor.Endostatin: A novel inhibitor of androgen receptor function in prostate cancer.The hedgehog/Gli signaling paradigm in prostate cancerInhibition of NF-kappa B signaling restores responsiveness of castrate-resistant prostate cancer cells to anti-androgen treatment by decreasing androgen receptor-variant expression.MED1 mediates androgen receptor splice variant induced gene expression in the absence of ligandFrequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors.A genome-wide survey over the ChIP-on-chip identified androgen receptor-binding genomic regions identifies a novel prostate cancer susceptibility locus at 12q13.13.Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.Hormones and prostate carcinogenesis: Androgens and estrogens.Androgen Receptor Enhances p27 Degradation in Prostate Cancer Cells through Rapid and Selective TORC2 Activation.Adrenal androgen concentrations increase during infancy in male rhesus macaques (Macaca mulatta)Animal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells.Outsmarting androgen receptor: creative approaches for targeting aberrant androgen signaling in advanced prostate cancer
P2860
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P2860
Mechanisms mediating androgen receptor reactivation after castration.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Mechanisms mediating androgen receptor reactivation after castration.
@ast
Mechanisms mediating androgen receptor reactivation after castration.
@en
type
label
Mechanisms mediating androgen receptor reactivation after castration.
@ast
Mechanisms mediating androgen receptor reactivation after castration.
@en
prefLabel
Mechanisms mediating androgen receptor reactivation after castration.
@ast
Mechanisms mediating androgen receptor reactivation after castration.
@en
P2860
P1433
P1476
Mechanisms mediating androgen receptor reactivation after castration.
@en
P2093
Steven P Balk
P2860
P356
10.1016/J.UROLONC.2008.03.021
P577
2009-01-01T00:00:00Z