Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction
about
NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressorRibosomal proteins as unrevealed caretakers for cellular stress and genomic instabilityDynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity.Simulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamicsThe COP9 signalosome subunit 6 (CSN6): a potential oncogeneNetwork modeling of MDM2 inhibitor-oxaliplatin combination reveals biological synergy in wt-p53 solid tumors.MDM2 promoter SNP285 and SNP309; phylogeny and impact on cancer riskEffects of the MDM2 promoter SNP285 and SNP309 on Sp1 transcription factor binding and cancer risk.The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer.p63 the guardian of human reproduction.MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid MalignanciesDNA damage-induced activation of ATM promotes β-TRCP-mediated Mdm2 ubiquitination and destructionQuercetin-induced apoptosis of HT-29 colon cancer cells via inhibition of the Akt-CSN6-Myc signaling axis.Regulation of p53: a collaboration between Mdm2 and Mdmx.p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3.The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.Hepatitis C virus Core overcomes all-trans retinoic acid-induced apoptosis in human hepatoma cells by inhibiting p14 expression via DNA methylation.
P2860
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P2860
Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Novel insights into the molecu ...... ubiquitination and destruction
@ast
Novel insights into the molecu ...... ubiquitination and destruction
@en
type
label
Novel insights into the molecu ...... ubiquitination and destruction
@ast
Novel insights into the molecu ...... ubiquitination and destruction
@en
prefLabel
Novel insights into the molecu ...... ubiquitination and destruction
@ast
Novel insights into the molecu ...... ubiquitination and destruction
@en
P2093
P2860
P921
P1433
P1476
Novel insights into the molecu ...... ubiquitination and destruction
@en
P2093
Hidefumi Fukushima
Hiroyuki Inuzuka
Shavali Shaik
P2860
P304
P356
10.18632/ONCOTARGET.101011
P407
P577
2010-11-01T00:00:00Z