Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators.
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Substrate binding by a bacterial ABC transporter involved in polysaccharide exportDevelopment of novel rifampicin-derived P-glycoprotein activators/inducers. synthesis, in silico analysis and application in the RBE4 cell model, using paraquat as substrateMultiple transport-active binding sites are available for a single substrate on human P-glycoprotein (ABCB1)Impact of germline and somatic missense variations on drug binding sitesThe amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transportP-glycoprotein induction in Caco-2 cells by newly synthetized thioxanthones prevents paraquat cytotoxicity.Combination of tunicamycin with anticancer drugs synergistically enhances their toxicity in multidrug-resistant human ovarian cystadenocarcinoma cells.Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy.Synthesis of 5,7-disubstituted-4-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amines as microtubule inhibitors.Fexofenadine hydrochloride in the treatment of allergic disease: a reviewThe ability of molecular docking to unravel the controversy and challenges related to P-glycoprotein--a well-known, yet poorly understood drug transporter.Targeting efflux pumps to overcome antifungal drug resistance.Insight into pleiotropic drug resistance ATP-binding cassette pump drug transport through mutagenesis of Cdr1p transmembrane domains.Molecular dynamics simulations of E. coli MsbA transmembrane domain: formation of a semipore structureMechanism-based categorization of aromatase inhibitors: a potential discovery and screening tool.Inhibition of P-glycoprotein by two artemisinin derivatives.The C-terminal domain of the nucleotide-binding domain protein Wzt determines substrate specificity in the ATP-binding cassette transporter for the lipopolysaccharide O-antigens in Escherichia coli serotypes O8 and O9a.Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein.Induction and activation of P-glycoprotein by dihydroxylated xanthones protect against the cytotoxicity of the P-glycoprotein substrate paraquat
P2860
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P2860
Identification and characterization of the binding sites of P-glycoprotein for multidrug resistance-related drugs and modulators.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Identification and characteriz ...... -related drugs and modulators.
@ast
Identification and characteriz ...... -related drugs and modulators.
@en
type
label
Identification and characteriz ...... -related drugs and modulators.
@ast
Identification and characteriz ...... -related drugs and modulators.
@en
prefLabel
Identification and characteriz ...... -related drugs and modulators.
@ast
Identification and characteriz ...... -related drugs and modulators.
@en
P2860
P356
P1476
Identification and characteriz ...... -related drugs and modulators.
@en
P2093
Ahmad R Safa
P2860
P356
10.2174/1568011043482142
P577
2004-01-01T00:00:00Z