Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.
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Synergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasis.Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectinsTrophoblast-uterine interactions at implantationHuman endometrial CD98 is essential for blastocyst adhesionElevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in miceSelectin-independent leukocyte rolling and adhesion in mice deficient in E-, P-, and L-selectin and ICAM-1.Autoperfused mouse flow chamber reveals synergistic neutrophil accumulation through P-selectin and E-selectin.P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow.Suppressive effects of selectin inhibitor SKK-60060 on the leucocyte infiltration during endotoxin induced uveitis.Evolutionary conservation of P-selectin glycoprotein ligand-1 primary structure and functionAbnormal P-selectin localization during megakaryocyte development determines thrombosis in the gata1low model of myelofibrosisCore 1-derived O-glycans are essential E-selectin ligands on neutrophils.Down-modulation of L-selectin by lipopolysaccharide is not required for lipopolysaccharide-induced expression of CD14 in mouse bone marrow granulocytesE-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling.GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice.Current concepts in lymphocyte homing and recirculation.Adhesion receptors on haematopoietic progenitor cells.Differential regulation of human and murine P-selectin expression and function in vivo.Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.Triple selectin knockout (ELP-/-) mice fail to develop OVA-induced acute asthma phenotypeSubset-specific reductions in lung lymphocyte accumulation following intratracheal antigen challenge in endothelial selectin-deficient mice.Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectinsRelative contributions of selectins and intercellular adhesion molecule-1 to tissue injury induced by immune complex deposition.Mobilization of stem/progenitor cells by sulfated polysaccharides does not require selectin presenceBlocking neutrophil integrin activation prevents ischemia-reperfusion injuryThe effect of soluble E-selectin on tumor progression and metastasis.Multi-Inhibitory Effects of A2A Adenosine Receptor Signaling on Neutrophil Adhesion Under FlowAnalytical cell adhesion chromatography reveals impaired persistence of metastatic cell rolling adhesion to P-selectin.Carbohydrate-carbohydrate interaction provides adhesion force and specificity for cellular recognition.Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus.P-Selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration.β3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammationNatural killer cells require selectins for suppression of subcutaneous tumorsREVIEW paper: pathophysiology of myocardial reperfusion injury: the role of genetically engineered mouse models.Homeostatic regulation of blood neutrophil counts.Transgenic models of nerve repair and nerve regeneration.Adhesion molecules in endometrial epithelium: tissue integrity and embryo implantation.PSGL-1-dependent myeloid leukocyte activation.Defining the functional boundaries of the murine α1,3-fucosyltransferase Fut7 reveals a remarkably compact locus.Regulation of neutrophil trafficking from the bone marrow.
P2860
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P2860
Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Multiple, targeted deficiencie ...... ctin in leukocyte recruitment.
@ast
Multiple, targeted deficiencie ...... ctin in leukocyte recruitment.
@en
type
label
Multiple, targeted deficiencie ...... ctin in leukocyte recruitment.
@ast
Multiple, targeted deficiencie ...... ctin in leukocyte recruitment.
@en
prefLabel
Multiple, targeted deficiencie ...... ctin in leukocyte recruitment.
@ast
Multiple, targeted deficiencie ...... ctin in leukocyte recruitment.
@en
P2093
P2860
P356
P1476
Multiple, targeted deficiencie ...... ectin in leukocyte recruitment
@en
P2093
D D Wagner
M Cummiskey
M Ullman-Culleré
P S Frenette
P2860
P304
11452-11457
P356
10.1073/PNAS.96.20.11452
P407
P577
1999-09-01T00:00:00Z