Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening.
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Clinical management of sleep disturbances in Alzheimer's disease: current and emerging strategiesPharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapyMolecular architecture of the mammalian circadian clockChronopharmacology: new insights and therapeutic implicationsSleep, circadian rhythms, and the pathogenesis of Alzheimer diseaseChemical chronobiology: Toward drugs manipulating time.Manipulating the circadian and sleep cycles to protect against metabolic diseaseHuman peripheral clocks: applications for studying circadian phenotypes in physiology and pathophysiologyEmerging models for the molecular basis of mammalian circadian timingCircadian dysfunction may be a key component of the non-motor symptoms of Parkinson's disease: insights from a transgenic mouse modelPhosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period lengthInhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney DiseaseCircadian pacemaking in cells and circuits of the suprachiasmatic nucleus.A strategy to identify dominant point mutant modifiers of a quantitative trait.Identification of small molecule activators of cryptochromeSmall molecule modifiers of circadian clocks.A Doubletime Nuclear Localization Signal Mediates an Interaction with Bride of Doubletime to Promote Circadian Function.The PXDLS linear motif regulates circadian rhythmicity through protein-protein interactionsSystems Biology-Derived Discoveries of Intrinsic Clocks.Global approaches for telling time: omics and the Arabidopsis circadian clockTranscriptional program of Kpna2/Importin-α2 regulates cellular differentiation-coupled circadian clock development in mammalian cells.Circadian clock disruption in neurodegenerative diseases: cause and effect?The hepatic circadian clock modulates xenobiotic metabolism in mice.Circadian metabolism in the light of evolutionDual attenuation of proteasomal and autophagic BMAL1 degradation in Clock Δ19/+ mice contributes to improved glucose homeostasisUbiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock.Monitoring cell-autonomous circadian clock rhythms of gene expression using luciferase bioluminescence reportersGenetic insights on sleep schedules: this time, it's PERsonal.Enhancement of NAD⁺-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells.Molecular Targets for Small-Molecule Modulators of Circadian Clocks.How to fix a broken clock.Clock-Enhancing Small Molecules and Potential Applications in Chronic Diseases and Aging.Circadian clock function in the mammalian ovary.Sleep- and circadian rhythm-associated pathways as therapeutic targets in bipolar disorder.Chronobesity: role of the circadian system in the obesity epidemic.The intricate dance of post-translational modifications in the rhythm of life.Regulating the Suprachiasmatic Nucleus (SCN) Circadian Clockwork: Interplay between Cell-Autonomous and Circuit-Level Mechanisms.The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome.Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development.Cell-based inhibitor screening identifies multiple protein kinases important for circadian clock oscillations.
P2860
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P2860
Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Identification of diverse modu ...... throughput chemical screening.
@ast
Identification of diverse modu ...... throughput chemical screening.
@en
type
label
Identification of diverse modu ...... throughput chemical screening.
@ast
Identification of diverse modu ...... throughput chemical screening.
@en
prefLabel
Identification of diverse modu ...... throughput chemical screening.
@ast
Identification of diverse modu ...... throughput chemical screening.
@en
P2093
P2860
P356
P1476
Identification of diverse modu ...... throughput chemical screening.
@en
P2093
Ethan Buhr
Hui-Lin Pan
Joseph S Takahashi
Keon-Hee Kim
Seung-Hee Yoo
Shuguang Wei
Yong-Sung Park
Zeng-You Ye
Zheng Chen
P2860
P304
P356
10.1073/PNAS.1118034108
P407
P577
2011-12-19T00:00:00Z