Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening. - Wikidata - wikimedia - TriplyDB

Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening.

Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening.

http://www.wikidata.org/entity/Q35657707

about

Clinical management of sleep disturbances in Alzheimer's disease: current and emerging strategies Pharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapy Molecular architecture of the mammalian circadian clock Chronopharmacology: new insights and therapeutic implications Sleep, circadian rhythms, and the pathogenesis of Alzheimer disease Chemical chronobiology: Toward drugs manipulating time.Manipulating the circadian and sleep cycles to protect against metabolic disease Human peripheral clocks: applications for studying circadian phenotypes in physiology and pathophysiology Emerging models for the molecular basis of mammalian circadian timing Circadian dysfunction may be a key component of the non-motor symptoms of Parkinson's disease: insights from a transgenic mouse model Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease Circadian pacemaking in cells and circuits of the suprachiasmatic nucleus.A strategy to identify dominant point mutant modifiers of a quantitative trait.Identification of small molecule activators of cryptochrome Small molecule modifiers of circadian clocks.A Doubletime Nuclear Localization Signal Mediates an Interaction with Bride of Doubletime to Promote Circadian Function.The PXDLS linear motif regulates circadian rhythmicity through protein-protein interactions Systems Biology-Derived Discoveries of Intrinsic Clocks.Global approaches for telling time: omics and the Arabidopsis circadian clock Transcriptional program of Kpna2/Importin-α2 regulates cellular differentiation-coupled circadian clock development in mammalian cells.Circadian clock disruption in neurodegenerative diseases: cause and effect?The hepatic circadian clock modulates xenobiotic metabolism in mice.Circadian metabolism in the light of evolution Dual attenuation of proteasomal and autophagic BMAL1 degradation in Clock Δ19/+ mice contributes to improved glucose homeostasis Ubiquitin ligase Siah2 regulates RevErbα degradation and the mammalian circadian clock.Monitoring cell-autonomous circadian clock rhythms of gene expression using luciferase bioluminescence reporters Genetic insights on sleep schedules: this time, it's PERsonal.Enhancement of NAD⁺-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells.Molecular Targets for Small-Molecule Modulators of Circadian Clocks.How to fix a broken clock.Clock-Enhancing Small Molecules and Potential Applications in Chronic Diseases and Aging.Circadian clock function in the mammalian ovary.Sleep- and circadian rhythm-associated pathways as therapeutic targets in bipolar disorder.Chronobesity: role of the circadian system in the obesity epidemic.The intricate dance of post-translational modifications in the rhythm of life.Regulating the Suprachiasmatic Nucleus (SCN) Circadian Clockwork: Interplay between Cell-Autonomous and Circuit-Level Mechanisms.The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome.Involvement of posttranscriptional regulation of Clock in the emergence of circadian clock oscillation during mouse development.Cell-based inhibitor screening identifies multiple protein kinases important for circadian clock oscillations.

P2860

Q26772851-F0B6F17F-3329-4E49-A9BC-D16607526BC5 Q26864230-0EDBD60A-8EC2-4BF4-9AB7-C70A7256180D Q27004052-A04ED0AA-89FD-4B57-BF2F-F9BAC117B93E Q27022411-64435E9D-2E1E-4347-9131-EE2F76168B63 Q27024779-E2506F4C-6D29-40C2-94DD-FDC7C7998828 Q27687867-07D8F95E-727B-4B4D-8FD0-3A1552CD452F Q28080813-5100FA0D-A7AA-411B-A158-527773C58534 Q28088613-586CC629-EB3D-4B7A-8AE7-24BA5EDEAEA8 Q28249506-FC60ED61-0366-46D4-8608-0CCBDF2C9BBC Q28384426-C341BADA-7C39-4AD3-B817-9ED9765A8EAA Q28590815-D36D1F0C-7A27-4034-B5A3-8A7B20B1ED49 Q28818297-B0D5DFD9-BE6B-421E-A39F-3DCDB25F1805 Q30581156-12CFAEB7-A07C-4A03-876B-8668CFE0CFE0 Q33784960-12734DA0-7891-4752-AE75-532A2C63A42E Q34288305-3A3BFA8B-064A-45E8-941A-97919D168ED1 Q34480532-A8BCDF3A-876A-4970-AA2C-A9097F6F1C68 Q34481028-356EAE7A-44E4-4694-8486-0BBA523BA01C Q34510063-5C5386AC-7E24-4FFB-B372-0338F0DEFC10 Q34551665-256F27F9-015B-4D0C-8F8E-C6573CE25745 Q34597407-D974C63A-C6D5-4813-9B0D-2D8E4FC60711 Q34601251-B4D122FA-85F9-40CD-8816-1B5357EB529C Q35128512-EFA85146-6761-477C-8825-0AAE1EFE0509 Q35138004-AE1733DE-72F7-4444-AD09-9907A3AEA567 Q35657123-D4076191-3E9A-49EA-BA64-E3E5A56C3670 Q35905811-57AF83EA-BB5E-4A6E-A95E-79801294B101 Q36155380-0C0673F9-87B7-4BB8-AF1B-4CD4DD730C12 Q36374997-3837CD48-1DEF-4335-B527-E47CD9E16E0D Q36405856-FC535BBD-D103-4046-93FA-E521344EBA3B Q36619057-20CC8FF6-0C34-44AA-80D1-60A62EEC5C29 Q36779787-68808B85-70DF-4BE1-8551-229E19BBB2D4 Q37375901-F73703F4-6659-4A61-BF8E-0B01139BBA39 Q37699510-0F89E187-824B-42DD-9E03-AEBCCE2F207A Q38264865-F1BC1357-FB5E-4B2E-B28D-84489C97EED8 Q38366298-C598E057-63E6-4A35-AA92-65F866D5BC90 Q38676128-D4893031-04DB-4A6F-BAC2-29370B4CA3B5 Q39030572-4E011D44-C780-4DD5-9EE5-A60AD1BBCA60 Q39066281-65B0B1D7-FE00-4813-9DE1-55631476E48A Q40204797-99C4A7EE-E5E6-47F3-B703-68560AC34227 Q41269902-1BCA2A7B-F5F5-4EEB-86E9-25A295EDC0A4 Q41293326-D7908E5D-009D-4EA3-959D-0271DD38CE7A

P2860

Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening.

http://www.wikidata.org/entity/Q35657707

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Identification of diverse modu ...... throughput chemical screening.

@ast

Identification of diverse modu ...... throughput chemical screening.

@en

type

label

Identification of diverse modu ...... throughput chemical screening.

@ast

Identification of diverse modu ...... throughput chemical screening.

@en

prefLabel

Identification of diverse modu ...... throughput chemical screening.

@ast

Identification of diverse modu ...... throughput chemical screening.

@en

P1433

Q35657707-65A3E17F-482F-476C-B019-0AFE609EB2C4

P1476

Q35657707-FF559845-17A5-4358-9444-358974AADCFE

P2093

Q35657707-0BC9D939-D3A4-4DE8-BE6C-C27972BED5EB

Q35657707-145F1399-D673-4C0E-BC9C-394D64DA1A85

Q35657707-70DBB7E2-21F6-4BDD-A440-8F87152CFF25

Q35657707-7F48D52C-0493-4F5E-928A-082204AC4BCE

Q35657707-9935A084-4A9E-43F6-BD79-4DAF775207D7

Q35657707-C8007E41-F97E-4901-8C88-DA07EA4CBC44

Q35657707-E0D61340-8FBD-4CFB-AD10-5A805A45670C

Q35657707-E16D8F3E-9AA1-4D96-B25C-278928DF3177

Q35657707-EAA216F9-D3B1-4DF4-A5DF-1404F8668CFF

P2860

Q35657707-00543FE4-3890-497C-875E-D3BC01922E06

Q35657707-034C6497-23F4-40B2-8A43-5857ABCF3B01

Q35657707-049D8F79-4094-474F-B2E6-7CC2EFDC378C

Q35657707-05EB0947-038F-47AB-BA67-C28141CA5B3D

Q35657707-09607324-C037-44E7-971D-D6D1508C3CE2

Q35657707-0B7EAE71-829F-469C-8BEB-C55FD7DF2CBE

Q35657707-0C3A76D8-B767-4864-A51A-1A230C3775BB

Q35657707-110FE555-FB11-423F-96B0-2C0B2D840C23

Q35657707-15BE0D7D-F57B-4335-ADD1-CAC52B7D05BE

Q35657707-16575F61-7303-4FC1-B38A-DA433B92AB31

P304

Q35657707-9E6D45B4-B6E4-4CB2-9B6B-975E2B2DFCCC

P31

Q35657707-56D6C67F-6ED2-45E2-936E-B720E915EAA3

P356

Q35657707-32EFB132-5407-4A0E-905A-8D5487195E3B

P407

Q35657707-73CAA045-0681-4657-8A83-257ABEEA6AEC

P433

Q35657707-6A30D430-2A77-44A3-9A42-B22E4F3DE95F

P478

Q35657707-60CB7F9E-25B2-46EF-AC89-426870557E4B

P577

Q35657707-B10FF728-233C-406A-A3C8-C3E3F6739324

P5875

Q35657707-0B53391E-4F3A-4E5E-A134-A75E259B734C

P698

Q35657707-48D2B244-70A0-478F-9886-EE25F03240C5

P921

Q35657707-C1F189CE-B52F-4DAE-BA7E-AD0CA807C09B

P932

Q35657707-2DBC117A-CFA8-4857-95B1-710E22F3CEC9

P356

PNAS.1118034108

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Identification of diverse modu ...... throughput chemical screening.

@en

P2093

Ethan Buhr

http://www.w3.org/2001/XMLSchema#string

Hui-Lin Pan

http://www.w3.org/2001/XMLSchema#string

Joseph S Takahashi

http://www.w3.org/2001/XMLSchema#string

Keon-Hee Kim

http://www.w3.org/2001/XMLSchema#string

Seung-Hee Yoo

http://www.w3.org/2001/XMLSchema#string

Shuguang Wei

http://www.w3.org/2001/XMLSchema#string

Yong-Sung Park

http://www.w3.org/2001/XMLSchema#string

Zeng-You Ye

http://www.w3.org/2001/XMLSchema#string

Zheng Chen

http://www.w3.org/2001/XMLSchema#string

P2860

High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase

Network features of the mammalian circadian clock

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.

Discovery of a proneurogenic, neuroprotective chemical

Obesity and metabolic syndrome in circadian Clock mutant mice

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair

Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex

A genome-wide RNAi screen for modifiers of the circadian clock in human cells

P304

101-106

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1118034108

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

109

http://www.w3.org/2001/XMLSchema#string

P577

2011-12-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51902504

http://www.w3.org/2001/XMLSchema#string

P698

22184224

http://www.w3.org/2001/XMLSchema#string

P921

circadian rhythm

P932

3252927

http://www.w3.org/2001/XMLSchema#string