Cyclin-dependent kinase 4-mediated phosphorylation inhibits Smad3 activity in cyclin D-overexpressing breast cancer cells.
about
CDK4 inhibition and doxorubicin mediate breast cancer cell apoptosis through Smad3 and survivin.Effects on human transcriptome of mutated BRCA1 BRCT domain: a microarray study.Single Chain Antibodies as Tools to Study transforming growth factor-β-Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens.Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cellsRevealing the anti-tumor effect of artificial miRNA p-27-5p on human breast carcinoma cell line T-47D.Phospho-specific Smad3 signaling: impact on breast oncogenesis.Inhibition of CDK-mediated phosphorylation of Smad3 results in decreased oncogenesis in triple negative breast cancer cells.CyclinD1 protein plays different roles in modulating chemoresponses in MCF7 and MDA-MB231 cellsHsa-miR-590-5p Interaction with SMAD3 Transcript Supports Its Regulatory Effect on The TGFβ Signaling PathwayEfficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models.TGF-β: duality of function between tumor prevention and carcinogenesis.Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice.Inhibition of CDK-mediated Smad3 phosphorylation reduces the Pin1-Smad3 interaction and aggressiveness of triple negative breast cancer cells.Cdk4/6 inhibition induces epithelial-mesenchymal transition and enhances invasiveness in pancreatic cancer cells.Multipotent neurogenic fate of mesenchymal stem cell is determined by Cdk4-mediated hypophosphorylation of Smad-STAT3.Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 Cancer cells with PX-866 and Raloxifene.Release the ink4a/arf growth suppression by "u" and "me"?Attenuation of Smad2 activity shows resistance to TGF-β signalling in mammary adenocarcinoma (MCF-7) cells.Synergistic effect of eribulin and CDK inhibition for the treatment of triple negative breast cancer.Comparative study of the effects of PEGylated interferon-α2a versus 5-fluorouracil on cancer stem cells in a rat model of hepatocellular carcinoma.Transforming Growth Factor-β Signaling Plays a Pivotal Role in the Interplay Between Osteosarcoma Cells and Their Microenvironment.Clinico-Pathological Importance of TGF-β/Phospho-Smad Signaling during Human Hepatic Fibrocarcinogenesis.
P2860
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P2860
Cyclin-dependent kinase 4-mediated phosphorylation inhibits Smad3 activity in cyclin D-overexpressing breast cancer cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Cyclin-dependent kinase 4-medi ...... xpressing breast cancer cells.
@ast
Cyclin-dependent kinase 4-medi ...... xpressing breast cancer cells.
@en
type
label
Cyclin-dependent kinase 4-medi ...... xpressing breast cancer cells.
@ast
Cyclin-dependent kinase 4-medi ...... xpressing breast cancer cells.
@en
prefLabel
Cyclin-dependent kinase 4-medi ...... xpressing breast cancer cells.
@ast
Cyclin-dependent kinase 4-medi ...... xpressing breast cancer cells.
@en
P2093
P2860
P1476
Cyclin-dependent kinase 4-medi ...... xpressing breast cancer cells.
@en
P2093
Anne Cooley
Jacqueline S Jeruss
Stanislav Zelivianski
P2860
P304
P356
10.1158/1541-7786.MCR-09-0537
P577
2010-08-24T00:00:00Z