Selective targeting of the mTORC1/2 protein kinase complexes leads to antileukemic effects in vitro and in vivo.
about
Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Targeting survival pathways in chronic myeloid leukaemia stem cellsNovel drug therapies in myeloid leukemia.Targeting the mTOR Pathway in Leukemia.Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-triggered TIAR-mediated suppression of translation.Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia.
P2860
Q34260622-F7C9DCAA-D307-47A7-9DB1-47E03BC3BA77Q34307356-319752D4-A2B8-444E-8AB2-9BD69F380212Q37122686-A8DB4790-5D69-412A-8B33-21CF49A31B6EQ38510486-1A865DE6-5F59-483B-9AD1-D843EF07C5B7Q38790630-683535D2-807F-44C2-9C6D-C81DEEBE672DQ38931383-7DD58ADF-E65A-4A7E-8CE2-7027D35DB5B8Q47598074-F3977185-5DE5-4752-AA3D-E030853743E4
P2860
Selective targeting of the mTORC1/2 protein kinase complexes leads to antileukemic effects in vitro and in vivo.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Selective targeting of the mTO ...... effects in vitro and in vivo.
@ast
Selective targeting of the mTO ...... effects in vitro and in vivo.
@en
type
label
Selective targeting of the mTO ...... effects in vitro and in vivo.
@ast
Selective targeting of the mTO ...... effects in vitro and in vivo.
@en
prefLabel
Selective targeting of the mTO ...... effects in vitro and in vivo.
@ast
Selective targeting of the mTO ...... effects in vitro and in vivo.
@en
P2093
P2860
P356
P1433
P1476
Selective targeting of the mTO ...... c effects in vitro and in vivo
@en
P2093
P2860
P2888
P356
10.1038/BCJ.2011.30
P577
2011-09-02T00:00:00Z