Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin
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The pore-forming toxin listeriolysin O mediates a novel entry pathway of L. monocytogenes into human hepatocytesMucociliary clearance defects in a murine in vitro model of pneumococcal airway infectionExpression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injuryStreptococcus pneumoniae ClpL modulates adherence to A549 human lung cells through Rap1/Rac1 activation.Moxifloxacin and cholesterol combined treatment of pneumococcal keratitisBacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage.Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity.Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue.PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins.Harvesting, identification and barrier function of human lung microvascular endothelial cellsChanges in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity.Listeriolysin O Affects the Permeability of Caco-2 Monolayer in a Pore-Dependent and Ca2+-Independent Manner.The role of anthrolysin O in gut epithelial barrier disruption during Bacillus anthracis infection.Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.How cholesterol regulates endothelial biomechanics.Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signalingPneumococcal Pneumolysin Induces DNA Damage and Cell Cycle ArrestDirect transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysinEvidence for Gardnerella vaginalis uptake and internalization by squamous vaginal epithelial cells: implications for the pathogenesis of bacterial vaginosisMini-review: novel therapeutic strategies to blunt actions of pneumolysin in the lungsProteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus.Vaginolysin drives epithelial ultrastructural responses to Gardnerella vaginalis.Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes.Cdc42 and the phosphatidylinositol 3-kinase-Akt pathway are essential for PspC-mediated internalization of pneumococci by respiratory epithelial cells.Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation.Extracellular beta-nicotinamide adenine dinucleotide (beta-NAD) promotes the endothelial cell barrier integrity via PKA- and EPAC1/Rac1-dependent actin cytoskeleton rearrangement.Suilysin remodels the cytoskeletons of human brain microvascular endothelial cells by activating RhoA and Rac1 GTPase.Pneumolysin released during Streptococcus pneumoniae autolysis is a potent activator of intracellular oxygen radical production in neutrophils.Heat incubation inactivates streptococcal exotoxins and recombinant cholesterol-dependent cytolysins: suilysin, pneumolysin and streptolysin O.Control of cytoskeletal dynamics during cellular responses to pore forming toxins.Host cell perforation by listeriolysin O (LLO) activates a Ca2+-dependent cPKC/Rac1/Arp2/3 signaling pathway that promotes L. monocytogenes internalization independently of membrane resealing.Astrocytic tissue remodeling by the meningitis neurotoxin pneumolysin facilitates pathogen tissue penetration and produces interstitial brain edema.RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins.Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit.
P2860
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P2860
Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin
@ast
Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin
@en
type
label
Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin
@ast
Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin
@en
prefLabel
Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin
@ast
Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin
@en
P2093
P2860
P356
P1476
Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin
@en
P2093
Asparouh I Iliev
Fred S Wouters
Jasmin Roya Djannatian
Roland Nau
Timothy J Mitchell
P2860
P304
P356
10.1073/PNAS.0608213104
P407
P577
2007-02-14T00:00:00Z