Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin - Wikidata - wikimedia - TriplyDB

Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin

Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin

http://www.wikidata.org/entity/Q35669797

about

The pore-forming toxin listeriolysin O mediates a novel entry pathway of L. monocytogenes into human hepatocytes Mucociliary clearance defects in a murine in vitro model of pneumococcal airway infection Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury Streptococcus pneumoniae ClpL modulates adherence to A549 human lung cells through Rap1/Rac1 activation.Moxifloxacin and cholesterol combined treatment of pneumococcal keratitis Bacterial cytolysin during meningitis disrupts the regulation of glutamate in the brain, leading to synaptic damage.Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity.Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue.PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins.Harvesting, identification and barrier function of human lung microvascular endothelial cells Changes in astrocyte shape induced by sublytic concentrations of the cholesterol-dependent cytolysin pneumolysin still require pore-forming capacity.Listeriolysin O Affects the Permeability of Caco-2 Monolayer in a Pore-Dependent and Ca2+-Independent Manner.The role of anthrolysin O in gut epithelial barrier disruption during Bacillus anthracis infection.Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.How cholesterol regulates endothelial biomechanics.Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling Pneumococcal Pneumolysin Induces DNA Damage and Cell Cycle Arrest Direct transmembrane interaction between actin and the pore-competent, cholesterol-dependent cytolysin pneumolysin Evidence for Gardnerella vaginalis uptake and internalization by squamous vaginal epithelial cells: implications for the pathogenesis of bacterial vaginosis Mini-review: novel therapeutic strategies to blunt actions of pneumolysin in the lungs Proteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus.Vaginolysin drives epithelial ultrastructural responses to Gardnerella vaginalis.Distinct Neurotoxicity Profile of Listeriolysin O from Listeria monocytogenes.Cdc42 and the phosphatidylinositol 3-kinase-Akt pathway are essential for PspC-mediated internalization of pneumococci by respiratory epithelial cells.Magnesium therapy improves outcome in Streptococcus pneumoniae meningitis by altering pneumolysin pore formation.Extracellular beta-nicotinamide adenine dinucleotide (beta-NAD) promotes the endothelial cell barrier integrity via PKA- and EPAC1/Rac1-dependent actin cytoskeleton rearrangement.Suilysin remodels the cytoskeletons of human brain microvascular endothelial cells by activating RhoA and Rac1 GTPase.Pneumolysin released during Streptococcus pneumoniae autolysis is a potent activator of intracellular oxygen radical production in neutrophils.Heat incubation inactivates streptococcal exotoxins and recombinant cholesterol-dependent cytolysins: suilysin, pneumolysin and streptolysin O.Control of cytoskeletal dynamics during cellular responses to pore forming toxins.Host cell perforation by listeriolysin O (LLO) activates a Ca2+-dependent cPKC/Rac1/Arp2/3 signaling pathway that promotes L. monocytogenes internalization independently of membrane resealing.Astrocytic tissue remodeling by the meningitis neurotoxin pneumolysin facilitates pathogen tissue penetration and produces interstitial brain edema.RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins.Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy Circuit.

P2860

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P2860

Cholesterol-dependent actin remodeling via RhoA and Rac1 activation by the Streptococcus pneumoniae toxin pneumolysin

http://www.wikidata.org/entity/Q35669797

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年论文

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name

Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin

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Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin

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Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin

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Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin

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Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin

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PNAS.0608213104

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Cholesterol-dependent actin re ...... s pneumoniae toxin pneumolysin

@en

P2093

Asparouh I Iliev

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Fred S Wouters

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Jasmin Roya Djannatian

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Roland Nau

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Timothy J Mitchell

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P2860

Rho GTPases have diverse effects on the organization of the actin filament system

Lipid rafts clustering and signalling by listeriolysin O

The low molecular mass GTP-binding protein Rho is affected by toxin A from Clostridium difficile

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

Structural basis of pore formation by the bacterial toxin pneumolysin

Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis

Identification of the region of rho involved in substrate recognition by Escherichia coli cytotoxic necrotizing factor 1 (CNF1).

Binding of cholesterol by sulfhydryl-activated cytolysins.

Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase.

Integrins regulate Rac targeting by internalization of membrane domains.

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2897-2902

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10.1073/PNAS.0608213104

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8

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104

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17301241

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1815278

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