Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.

Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.

Item
http://www.wikidata.org/entity/Q35670413
Reduction of apoptosis by proanthocyanidin-induced autophagy in the human gastric cancer cell line MGC-803.Activity-Based Proteomics Reveals Heterogeneous Kinome and ATP-Binding Proteome Responses to MEK Inhibition in KRAS Mutant Lung Cancer.Blockade efficacy of MEK/ERK-dependent autophagy enhances PI3K/Akt inhibitor NVP-BKM120's therapeutic effectiveness in lung cancer cellsPhosphatidyl inositol-3 kinase (PIK3CA) E545K mutation confers cisplatin resistance and a migratory phenotype in cervical cancer cells.Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities.Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition.Allosteric modulators of MEK1: drug design and discovery.Modulating lysosomal function through lysosome membrane permeabilization or autophagy suppression restores sensitivity to cisplatin in refractory non-small-cell lung cancer cells.Proteomics Insights into Autophagy.Inhibition of HSP90 sensitizes a novel Raf/ERK dual inhibitor CY-9d in triple-negative breast cancer cells.Desethylamiodarone-A metabolite of amiodarone-Induces apoptosis on T24 human bladder cancer cells via multiple pathways.HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC.
P2860

Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.

Item
http://www.wikidata.org/entity/Q35670413
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Enhancing therapeutic efficacy ...... ng in human lung cancer cells.
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Enhancing therapeutic efficacy ...... ng in human lung cancer cells.
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Enhancing therapeutic efficacy ...... ng in human lung cancer cells.
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Enhancing therapeutic efficacy ...... ng in human lung cancer cells.
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Enhancing therapeutic efficacy ...... ng in human lung cancer cells.
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Enhancing therapeutic efficacy ...... ng in human lung cancer cells.
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Enhancing therapeutic efficacy ...... ng in human lung cancer cells.
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10.1016/J.CANLET.2015.04.028
P407
P433
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P932