The role of subunit assembly in peripherin-2 targeting to rod photoreceptor disk membranes and retinitis pigmentosa.
about
Dominant negative mechanism underlies autosomal dominant Stargardt-like macular dystrophy linked to mutations in ELOVL4A monogenic dominant mutation in Rom1 generated by N-ethyl-N-nitrosourea mutagenesis causes retinal degeneration in miceDivergence of dim-light vision among bats (order: Chiroptera) as estimated by molecular and electrophysiological methods.Differential requirements for retinal degeneration slow intermolecular disulfide-linked oligomerization in rods versus conesRole of the second intradiscal loop of peripherin/rds in homo and hetero associations.Peripherin-2 and Rom-1 have opposing effects on rod outer segment targeting of retinitis pigmentosa-linked peripherin-2 mutants.Uncoupling of photoreceptor peripherin/rds fusogenic activity from biosynthesis, subunit assembly, and targeting: a potential mechanism for pathogenic effects.The cell biology of visionIn situ visualization of protein interactions in sensory neurons: glutamic acid-rich proteins (GARPs) play differential roles for photoreceptor outer segment scaffoldingThe function of oligomerization-incompetent RDS in rodsLight regulates the ciliary protein transport and outer segment disc renewal of mammalian photoreceptors.Prominin-1 localizes to the open rims of outer segment lamellae in Xenopus laevis rod and cone photoreceptors.Characterization of peripherin/rds and rom-1 transport in rod photoreceptors of transgenic and knockout animalsRetinal Degeneration Slow (RDS) Glycosylation Plays a Role in Cone Function and in the Regulation of RDS·ROM-1 Protein Complex Formation.Modeling the flexural rigidity of rod photoreceptorsTransgenic animal studies of human retinal disease caused by mutations in peripherin/rds.PRPH2/RDS and ROM-1: Historical context, current views and future considerations.A novel mutation in Prph2, a gene regulated by Nr2e3, causes retinal degeneration and outer-segment defects similar to Nr2e3 ( rd7/rd7 ) retinas.The C terminus of peripherin/rds participates in rod outer segment targeting and alignment of disk incisures.Characterization of human cone phosphodiesterase-6 ectopically expressed in Xenopus laevis rodsOuter segment oligomerization of Rds: evidence from mouse models and subcellular fractionation.An unconventional secretory pathway mediates the cilia targeting of peripherin/rdsMolecular basis for photoreceptor outer segment architecture.Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa.Temporal progression of PARP activity in the Prph2 mutant rd2 mouse: Neuroprotective effects of the PARP inhibitor PJ34.The Cys214-->Ser mutation in peripherin/rds causes a loss-of-function phenotype in transgenic miceAn inducible amphipathic helix within the intrinsically disordered C terminus can participate in membrane curvature generation by peripherin-2/rds.
P2860
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P2860
The role of subunit assembly in peripherin-2 targeting to rod photoreceptor disk membranes and retinitis pigmentosa.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
The role of subunit assembly i ...... anes and retinitis pigmentosa.
@ast
The role of subunit assembly i ...... anes and retinitis pigmentosa.
@en
type
label
The role of subunit assembly i ...... anes and retinitis pigmentosa.
@ast
The role of subunit assembly i ...... anes and retinitis pigmentosa.
@en
prefLabel
The role of subunit assembly i ...... anes and retinitis pigmentosa.
@ast
The role of subunit assembly i ...... anes and retinitis pigmentosa.
@en
P2093
P2860
P356
P1476
The role of subunit assembly i ...... ranes and retinitis pigmentosa
@en
P2093
Beatrice M Tam
Christopher J R Loewen
David S Papermaster
Robert S Molday
P2860
P304
P356
10.1091/MBC.E03-02-0077
P577
2003-05-03T00:00:00Z