Structural basis for gating charge movement in the voltage sensor of a sodium channel
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Voltage-Controlled Enzymes: The New JanusBifronsThe hitchhiker's guide to the voltage-gated sodium channel galaxyMolecular pathophysiology and pharmacology of the voltage-sensing module of neuronal ion channelsThe Hodgkin-Huxley heritage: from channels to circuitsTheoretical and simulation studies on voltage-gated sodium channelsNa+ channel function, regulation, structure, trafficking and sequestrationAn Integrated Framework Advancing Membrane Protein Modeling and DesignStructural Refinement of Proteins by Restrained Molecular Dynamics Simulations with Non-interacting Molecular Fragments.Deciphering voltage-gated Na(+) and Ca(2+) channels by studying prokaryotic ancestorsStructural Basis for Pharmacology of Voltage-Gated Sodium and Calcium ChannelsVoltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) familyStructure and function of voltage-gated sodium channels at atomic resolution.Pathogenic mechanism of recurrent mutations of SCN8A in epileptic encephalopathyGating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states.Modeling and simulation of ion channels.Hydrophobic plug functions as a gate in voltage-gated proton channels.Knock-in model of Dravet syndrome reveals a constitutive and conditional reduction in sodium current.Cardiac Na Channels: Structure to FunctionModulation of a voltage-gated Na+ channel by sevoflurane involves multiple sites and distinct mechanismsRobust and accurate prediction of residue-residue interactions across protein interfaces using evolutionary information.Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac.Molecular dynamics study of binding of µ-conotoxin GIIIA to the voltage-gated sodium channel Na(v)1.4.Probing α-3(10) transitions in a voltage-sensing S4 helixVoltage-gated sodium channels at 60: structure, function and pathophysiology.Interfacial gating triad is crucial for electromechanical transduction in voltage-activated potassium channels.Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cellsCapturing distinct KCNQ2 channel resting states by metal ion bridges in the voltage-sensor domain.A novel SCN9A mutation responsible for primary erythromelalgia and is resistant to the treatment of sodium channel blockersBacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart.Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy.A specialized molecular motion opens the Hv1 voltage-gated proton channel.Conformational rearrangements in the transmembrane domain of CNGA1 channels revealed by single-molecule force spectroscopy.Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel.Voltage Sensing in Membranes: From Macroscopic Currents to Molecular MotionsComputation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4.Computer Simulations of Voltage-Gated Cation ChannelsHinge-bending motions in the pore domain of a bacterial voltage-gated sodium channelA Large and Phylogenetically Diverse Class of Type 1 Opsins Lacking a Canonical Retinal Binding SiteOpposite Effects of the S4-S5 Linker and PIP(2) on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels.The Biophysical Basis Underlying Gating Changes in the p.V1316A Mutant Nav1.7 Channel and the Molecular Pathogenesis of Inherited Erythromelalgia.
P2860
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P2860
Structural basis for gating charge movement in the voltage sensor of a sodium channel
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Structural basis for gating charge movement in the voltage sensor of a sodium channel
@ast
Structural basis for gating charge movement in the voltage sensor of a sodium channel
@en
type
label
Structural basis for gating charge movement in the voltage sensor of a sodium channel
@ast
Structural basis for gating charge movement in the voltage sensor of a sodium channel
@en
prefLabel
Structural basis for gating charge movement in the voltage sensor of a sodium channel
@ast
Structural basis for gating charge movement in the voltage sensor of a sodium channel
@en
P2093
P2860
P50
P356
P1476
Structural basis for gating charge movement in the voltage sensor of a sodium channel
@en
P2093
Paul G DeCaen
Ruth E Westenbroek
Todd Scheuer
William A Catterall
P2860
P304
P356
10.1073/PNAS.1118434109
P407
P577
2011-12-12T00:00:00Z