Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease.
about
DNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiaeMutagenic effects of abasic and oxidized abasic lesions in Saccharomyces cerevisiae.A yeast homologue of the human phosphotyrosyl phosphatase activator PTPA is implicated in protection against oxidative DNA damage induced by the model carcinogen 4-nitroquinoline 1-oxide.The Saccharomyces cerevisiae IMP2 gene encodes a transcriptional activator that mediates protection against DNA damage caused by bleomycin and other oxidants.Pir1p mediates translocation of the yeast Apn1p endonuclease into the mitochondria to maintain genomic stabilityThe 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae.Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sitesIncision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNADNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiaeRequirement for abasic endonuclease gene homologues in Arabidopsis seed development.Overexpression of enzymes that repair endogenous damage to DNA.Imbalanced base excision repair increases spontaneous mutation and alkylation sensitivity in Escherichia coli.Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNADifference between deoxyribose- and tetrahydrofuran-type abasic sites in the in vivo mutagenic responses in yeast.Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites.Regulation of eukaryotic abasic endonucleases and their role in genetic stabilityGeneration of a strong mutator phenotype in yeast by imbalanced base excision repair.Trans-complementation by human apurinic endonuclease (Ape) of hypersensitivity to DNA damage and spontaneous mutator phenotype in apn1-yeast.YqfS from Bacillus subtilis is a spore protein and a new functional member of the type IV apurinic/apyrimidinic-endonuclease family.Biochemical reconstitution of abasic DNA lesion replication in Xenopus extractsMutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase.Balancing repair and tolerance of DNA damage caused by alkylating agentsHigh levels of transcription stimulate transversions at GC base pairs in yeast.The role of base excision repair genes OGG1, APN1 and APN2 in benzo[a]pyrene-7,8-dione induced p53 mutagenesis.Overexpression of a Rrp1 transgene reduces the somatic mutation and recombination frequency induced by oxidative DNA damage in Drosophila melanogaster.Base excision repair intermediates as topoisomerase II poisons.Characterization of the promoter region of the human apurinic endonuclease gene (APE).On the mechanism of preferential incorporation of dAMP at abasic sites in translesional DNA synthesis. Role of proofreading activity of DNA polymerase and thermodynamic characterization of model template-primers containing an abasic site.Characterisation of new substrate specificities of Escherichia coli and Saccharomyces cerevisiae AP endonucleases.Replication bypass and mutagenic effect of alpha-deoxyadenosine site-specifically incorporated into single-stranded vectors.Expression of yeast apurinic/apyrimidinic endonuclease (APN1) protects lung epithelial cells from bleomycin toxicity.The apurinic-apyrimidinic endonuclease IV family of DNA repair enzymes.Specificities of the Saccharomyces cerevisiae rad6, rad18, and rad52 mutators exhibit different degrees of dependence on the REV3 gene product, a putative nonessential DNA polymerase.Escherichia coli apurinic-apyrimidinic endonucleases enhance the turnover of the adenine glycosylase MutY with G:A substrates.Abasic translesion synthesis by DNA polymerase beta violates the "A-rule". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts.Translesional synthesis on DNA templates containing a single abasic site. A mechanistic study of the "A rule".
P2860
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P2860
Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Specificity of the mutator cau ...... e major apurinic endonuclease.
@ast
Specificity of the mutator cau ...... e major apurinic endonuclease.
@en
type
label
Specificity of the mutator cau ...... e major apurinic endonuclease.
@ast
Specificity of the mutator cau ...... e major apurinic endonuclease.
@en
prefLabel
Specificity of the mutator cau ...... e major apurinic endonuclease.
@ast
Specificity of the mutator cau ...... e major apurinic endonuclease.
@en
P2093
P2860
P356
P1476
Specificity of the mutator cau ...... e major apurinic endonuclease.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.17.8165
P407
P577
1994-08-01T00:00:00Z