Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunity
about
The role of pattern-recognition receptors in graft-versus-host disease and graft-versus-leukemia after allogeneic stem cell transplantationAcute graft-versus-host disease: a bench-to-bedside update.Danger Signals and Graft-versus-host Disease: Current Understanding and Future PerspectivesAdvances in graft-versus-host disease biology and therapy.Antibodies against Marinobacter algicola and Salmonella typhimurium flagellins do not cross-neutralize TLR5 activationNon-invasive imaging of allogeneic transplanted skin graft by 131I-anti-TLR5 mAbVarious forms of tissue damage and danger signals following hematopoietic stem-cell transplantation.Recombinant TLR5 agonist CBLB502 promotes NK cell-mediated anti-CMV immunity in mice.A GMCSF and IL7 fusion cytokine leads to functional thymic-dependent T-cell regeneration in age-associated immune deficiencyThe gastrointestinal tract: properties and role in allogeneic hematopoietic stem cell transplantation.TLR stimulation of bone marrow lymphoid precursors from childhood acute leukemia modifies their differentiation potentials.Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathwayrFliC prolongs allograft survival in association with the activation of recipient Tregs in a TLR5-dependent manner.Pathogenesis of graft-versus-host disease: innate immunity amplifying acute alloimmune responses.Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease.Sensing danger: toll-like receptors and outcome in allogeneic hematopoietic stem cell transplantation.In vivo Toll-like receptor 5 (TLR5) imaging with radiolabeled anti-TLR5 monoclonal antibody in rapamycin-treated mouse allogeneic skin transplantation model.Toll-like receptor 5 signaling restrains T-cell/natural killer T-cell activation and protects against concanavalin A-induced hepatic injury.Regulatory T-cell impairment in cystic fibrosis patients with chronic pseudomonas infection.A specific Toll-like receptor profile on T lymphocytes and values of monocytes correlate with bacterial, fungal, and cytomegalovirus infections in the early period of allogeneic stem cell transplantation.PD-1 and CTLA-4 up regulation on donor T cells is insufficient to prevent GvHD in allo-HSCT recipientsAnti-metastatic immunotherapy based on mucosal administration of flagellin and immunomodulatory P10.
P2860
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P2860
Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunity
description
2011 nî lūn-bûn
@nan
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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2011年论文
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2011年论文
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name
Flagellin, a TLR5 agonist, red ...... e enhancing antiviral immunity
@ast
Flagellin, a TLR5 agonist, red ...... e enhancing antiviral immunity
@en
type
label
Flagellin, a TLR5 agonist, red ...... e enhancing antiviral immunity
@ast
Flagellin, a TLR5 agonist, red ...... e enhancing antiviral immunity
@en
prefLabel
Flagellin, a TLR5 agonist, red ...... e enhancing antiviral immunity
@ast
Flagellin, a TLR5 agonist, red ...... e enhancing antiviral immunity
@en
P2093
P2860
P356
P1476
Flagellin, a TLR5 agonist, red ...... e enhancing antiviral immunity
@en
P2093
Andrew T Gewirtz
Brian P Pollack
Ebenezer David
Edmund K Waller
John D Roback
Malefa L Tselanyane
Mohammad S Hossain
P2860
P304
P356
10.4049/JIMMUNOL.1101334
P407
P577
2011-10-17T00:00:00Z