The laforin-malin complex negatively regulates glycogen synthesis by modulating cellular glucose uptake via glucose transporters.
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Minireview: hey U(PS): metabolic and proteolytic homeostasis linked via AMPK and the ubiquitin proteasome system.The recruitment of AMP-activated protein kinase to glycogen is regulated by autophosphorylation.Deciphering the role of malin in the lafora progressive myoclonus epilepsyActivation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease.Laforin-malin complex degrades polyglucosan bodies in concert with glycogen debranching enzyme and brain isoform glycogen phosphorylasePhenotype variations in Lafora progressive myoclonus epilepsy: possible involvement of genetic modifiers?The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations.Changing shapes of glycogen-autophagy nexus in neurons: perspective from a rare epilepsy.Loss of neuronatin promotes "browning" of primary mouse adipocytes while reducing Glut1-mediated glucose disposal.Suppression of leptin signaling reduces polyglucosan inclusions and seizure susceptibility in a mouse model for Lafora disease.Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux.Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease.Low glucose transporter SLC2A5-inhibited human normal adjacent lung adenocarcinoma cytoplasmic pro-B cell development mechanism network.
P2860
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P2860
The laforin-malin complex negatively regulates glycogen synthesis by modulating cellular glucose uptake via glucose transporters.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The laforin-malin complex nega ...... take via glucose transporters.
@ast
The laforin-malin complex nega ...... take via glucose transporters.
@en
type
label
The laforin-malin complex nega ...... take via glucose transporters.
@ast
The laforin-malin complex nega ...... take via glucose transporters.
@en
prefLabel
The laforin-malin complex nega ...... take via glucose transporters.
@ast
The laforin-malin complex nega ...... take via glucose transporters.
@en
P2093
P2860
P356
P1476
The laforin-malin complex nega ...... take via glucose transporters.
@en
P2093
Pankaj Kumar Singh
Subramaniam Ganesh
Sweta Singh
P2860
P304
P356
10.1128/MCB.06353-11
P407
P577
2011-11-28T00:00:00Z