Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma - Wikidata - wikimedia - TriplyDB

Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

http://www.wikidata.org/entity/Q35700114

about

Cellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressor Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma Extensive survey of STAT6 expression in a large series of mesenchymal tumors.Cyclin-dependent kinase 11 (CDK11) is crucial in the growth of liposarcoma cells Identification of a gene expression driven progression pathway in myxoid liposarcoma.New therapeutic targets in soft tissue sarcoma.Clinical relevance of peroxisome proliferator-activated receptor-gamma expression in myxoid liposarcoma.Epistatic interaction between the lipase-encoding genes Pnpla2 and Lipe causes liposarcoma in mice.The molecular landscape of extraskeletal osteosarcoma: A clinicopathological and molecular biomarker study.Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3 translocation.Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas Prognostic implications of PIK3CA amplification in curatively resected liposarcoma Axitinib Has Antiangiogenic and Antitumorigenic Activity in Myxoid Liposarcoma miR-135b, a key regulator of malignancy, is linked to poor prognosis in human myxoid liposarcoma.HDACi inhibits liposarcoma via targeting of the MDM2-p53 signaling axis and PTEN, irrespective of p53 mutational status.Multi-platform profiling of over 2000 sarcomas: identification of biomarkers and novel therapeutic targets.Recent translational research into targeted therapy for liposarcoma.High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth.Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy.Establishing a patient-derived xenograft model of human myxoid and round-cell liposarcoma.Tumour-associated macrophages correlate with poor prognosis in myxoid liposarcoma and promote cell motility and invasion via the HB-EGF-EGFR-PI3K/Akt pathways.Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets.Clinical and Molecular Spectrum of Liposarcoma.

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P2860

Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

http://www.wikidata.org/entity/Q35700114

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

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Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

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Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

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Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

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Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

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Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

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MODPATHOL.2011.148

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Modern Pathology

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Involvement of the PI3K/Akt pathway in myxoid/round cell liposarcoma

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Aviad Hoffman

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Dina Lev

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Elizabeth G Demicco

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Judith V M G Bovée

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Keila E Torres

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Markus P Ghadimi

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Svetlana Bolshakov

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Tingsheng Peng

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Wei-Lien Wang

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P2860

Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

PI3K pathway alterations in cancer: variations on a theme

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors.

Rapid KRAS, EGFR, BRAF and PIK3CA mutation analysis of fine needle aspirates from non-small-cell lung cancer using allele-specific qPCR.

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: a molecular and clinicopathologic study of 82 cases.

Myxoid/round cell liposarcoma of the extremities. A clinicopathologic study of 29 cases with particular attention to extent of round cell liposarcoma.

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