A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. - Wikidata - wikimedia - TriplyDB

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

http://www.wikidata.org/entity/Q35702861

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Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data Microglial malfunction: the third rail in the development of Alzheimer's disease.CD33 modulates TREM2: convergence of Alzheimer loci.Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease.TREM2 in Neurodegenerative Diseases.UNC5C variants are associated with cerebral amyloid angiopathy.Genome research in pre-dementia stages of Alzheimer's disease.Genetic epistasis regulates amyloid deposition in resilient aging.Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB.The role of peripheral immune cells in the CNS in steady state and disease.A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.Levels of soluble TREM-1 in children with newly diagnosed type 1 diabetes and their siblings without type 1 diabetes: a Danish case-control study.Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain.Convergent Genetic and Expression Datasets Highlight TREM2 in Parkinson's Disease Susceptibility.The roles of inflammation and immune mechanisms in Alzheimer's disease.A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.No association of TREM1 rs6910730 and TREM2 rs7759295 with Alzheimer disease.TREM1 facilitates microglial phagocytosis of amyloid beta.Targeting microglia for the treatment of Alzheimer's Disease.TREM1: A Potential Therapeutic Target For Alzheimer's Disease.

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P2860

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

http://www.wikidata.org/entity/Q35702861

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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name

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

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A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

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type

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A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

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A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

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prefLabel

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

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A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

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Annals of Neurology

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A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.

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Charles C White

http://www.w3.org/2001/XMLSchema#string

Denis A Evans

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Elizabeth M Bradshaw

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Gail Chan

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Joseph M Replogle

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Julie A Schneider

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Lori B Chibnik

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Philip L De Jager

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Phoebe A Winn

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Reisa A Sperling

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P2860

TREM2 Variants in Alzheimer's Disease

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44

PLINK: a tool set for whole-genome association and population-based linkage analyses

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

Principal components analysis corrects for stratification in genome-wide association studies

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.

Adjusting batch effects in microarray expression data using empirical Bayes methods

TREM2 is upregulated in amyloid plaque-associated microglia in aged APP23 transgenic mice.

P304

469-477

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scholarly article

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10.1002/ANA.24337

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3

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77

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David A Bennett

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2015-03-01T00:00:00Z

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25545807

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Alzheimer's disease

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4461024

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