CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer. - Wikidata - wikimedia - TriplyDB

CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer.

CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer.

http://www.wikidata.org/entity/Q35709153

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Molecular cues on obesity signals, tumor markers and endometrial cancer.The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis Impaired tumor angiogenesis and VEGF-induced pathway in endothelial CD146 knockout mice.Targeting autophagic cancer stem-cells to reverse chemoresistance in human triple negative breast cancer Biomarkers to Target Heterogeneous Breast Cancer Stem Cells Neither epithelial nor mesenchymal circulating tumor cells isolated from breast cancer patients are tumorigenic in NOD-scid Il2rgnull mice.CD146 expression in human breast cancer cell lines induces phenotypic and functional changes observed in Epithelial to Mesenchymal Transition Human developmental chondrogenesis as a basis for engineering chondrocytes from pluripotent stem cells.Prognostic Relevance of Circulating Tumor Cells in Molecular Subtypes of Breast Cancer.Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cells.CD133+ ovarian cancer stem-like cells promote non-stem cancer cell metastasis via CCL5 induced epithelial-mesenchymal transition.METCAM/MUC18 is a novel tumor and metastasis suppressor for the human ovarian cancer SKOV3 cells CD146 as an adverse prognostic factor in uterine sarcoma.CD146 expression correlates with epithelial-mesenchymal transition markers and a poor prognosis in gastric cancer TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells.Bone morphogenetic protein 7 sensitizes O6-methylguanine methyltransferase expressing-glioblastoma stem cells to clinically relevant dose of temozolomide.Decreased expression of mucin 18 is associated with unfavorable postoperative prognosis in patients with clear cell renal cell carcinoma Targeting CD146 with a 64Cu-labeled antibody enables in vivo immunoPET imaging of high-grade gliomas.Inhibition of ERRα suppresses epithelial mesenchymal transition of triple negative breast cancer cells by directly targeting fibronectin.CD146 promotes metastasis and predicts poor prognosis of hepatocellular carcinoma Oxidants, antioxidants and the current incurability of metastatic cancers.CD146 is a potential marker for the diagnosis of malignancy in cervical and endometrial cancer Targeting endothelial CD146 attenuates neuroinflammation by limiting lymphocyte extravasation to the CNS.Integrin αvβ3 and fibronectin upregulate Slug in cancer cells to promote clot invasion and metastasis.Reduced CD146 expression promotes tumorigenesis and cancer stemness in colorectal cancer through activating Wnt/β-catenin signaling.Lovastatin Reduces Stemness via Epigenetic Reprograming of BMP2 and GATA2 in Human Endometrium and Endometriosis.Clinical value of circulating endothelial cells and of soluble CD146 levels in patients undergoing surgery for non-small cell lung cancer.NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling.MDA-9/Syntenin (SDCBP) modulates small GTPases RhoA and Cdc42 via transforming growth factor β1 to enhance epithelial-mesenchymal transition in breast cancer.Role of the host stroma in cancer and its therapeutic significance.Melanoma biomolecules: independently identified but functionally intertwined.Epithelial-mesenchymal transition as a fundamental underlying pathogenic process in COPD airways: fibrosis, remodeling and cancer.ImmunoPET imaging of CD146 in murine models of intrapulmonary metastasis of non-small cell lung cancer.Inhibiting CD146 by its Monoclonal Antibody AA98 Improves Radiosensitivity of Cervical Cancer Cells.Anti-Metastatic and Anti-Invasion Effects of a Specific Anti-MUC18 scFv Antibody on Breast Cancer Cells.Ectopic expression of MCAM/MUC18 increases in vitro motility and invasiveness, but decreases in vivo tumorigenesis and metastasis of a mouse melanoma K1735-9 subline in a syngeneic mouse model.ImmunoPET for assessing the differential uptake of a CD146-specific monoclonal antibody in lung cancer.Canine cell line, IPC-366, as a good model for the study of inflammatory breast cancer.CD146 attenuation in cancer-associated fibroblasts promotes pancreatic cancer progression.PD-L1 induces epithelial-to-mesenchymal transition via activating SREBP-1c in renal cell carcinoma.

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CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer.

http://www.wikidata.org/entity/Q35709153

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CD146, an epithelial-mesenchym ...... triple-negative breast cancer.

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CD146, an epithelial-mesenchym ...... triple-negative breast cancer.

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CD146, an epithelial-mesenchym ...... triple-negative breast cancer.

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CD146, an epithelial-mesenchym ...... triple-negative breast cancer.

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CD146, an epithelial-mesenchym ...... triple-negative breast cancer.

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CD146, an epithelial-mesenchym ...... triple-negative breast cancer.

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PNAS.1111053108

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Proceedings of the National Academy of Sciences of the United States of America

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CD146, an epithelial-mesenchym ...... triple-negative breast cancer.

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Di Lu

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Dongling Yang

http://www.w3.org/2001/XMLSchema#string

Hongxia Duan

http://www.w3.org/2001/XMLSchema#string

Jing Feng

http://www.w3.org/2001/XMLSchema#string

Li Fu

http://www.w3.org/2001/XMLSchema#string

Qiqun Zeng

http://www.w3.org/2001/XMLSchema#string

Weidong Li

http://www.w3.org/2001/XMLSchema#string

Xiyun Yan

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Yongting Luo

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Zhenzhen Wu

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P2860

Global cancer statistics

Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma

The epithelial-mesenchymal transition generates cells with properties of stem cells

CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

Epithelial-mesenchymal transitions in development and disease

Endothelial CD146 is required for in vitro tumor-induced angiogenesis: the role of a disulfide bond in signaling and dimerization

A causal role for E-cadherin in the transition from adenoma to carcinoma

Rho GTPases and cell migration

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