Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.
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Neurofibromatosis: chronological history and current issues.Discovery of a small molecule targeting IRA2 deletion in budding yeast and neurofibromin loss in malignant peripheral nerve sheath tumor cellsNf1 RasGAP inhibition of LIMK2 mediates a new cross-talk between Ras and Rho pathwaysNatural products reveal cancer cell dependence on oxysterol-binding proteins.Quantitative analysis of F-actin redistribution in astrocytoma cells treated with candidate pharmaceuticals.Small molecule schweinfurthins selectively inhibit cancer cell proliferation and mTOR/AKT signaling by interfering with trans-Golgi-network trafficking.Relevance of the C-5 position to schweinfurthin induced cytotoxicity.RNA interference‑mediated knockdown of translationally controlled tumor protein induces apoptosis, and inhibits growth and invasion in glioma cellsFunctional evaluation of a fluorescent schweinfurthin: mechanism of cytotoxicity and intracellular quantification.Whole Exome Sequencing Reveals the Order of Genetic Changes during Malignant Transformation and Metastasis in a Single Patient with NF1-plexiform NeurofibromaCalcium and P-glycoprotein independent synergism between schweinfurthins and verapamil.Regulation of cholesterol biosynthesis and cancer signalingAnticancer activity of taraxerol acetate in human glioblastoma cells and a mouse xenograft model via induction of autophagy and apoptotic cell death, cell cycle arrest and inhibition of cell migration3-Deoxyschweinfurthin B Lowers Cholesterol Levels by Decreasing Synthesis and Increasing Export in Cultured Cancer Cell Lines.Pleiotropic effects of a schweinfurthin on isoprenoid homeostasis
P2860
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P2860
Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
@zh-cn
name
Schweinfurthin A selectively i ...... in a NF1-GRD-dependent manner.
@ast
Schweinfurthin A selectively i ...... in a NF1-GRD-dependent manner.
@en
type
label
Schweinfurthin A selectively i ...... in a NF1-GRD-dependent manner.
@ast
Schweinfurthin A selectively i ...... in a NF1-GRD-dependent manner.
@en
prefLabel
Schweinfurthin A selectively i ...... in a NF1-GRD-dependent manner.
@ast
Schweinfurthin A selectively i ...... in a NF1-GRD-dependent manner.
@en
P2093
P2860
P1476
Schweinfurthin A selectively i ...... in a NF1-GRD-dependent manner
@en
P2093
Claudia A Lipschultz
David F Wiemer
Demirkan B Gürsel
Jessica C Walrath
Karlyne M Reilly
Robert G Tuskan
Stephen J Lockett
Thomas J Turbyville
P2860
P304
P356
10.1158/1535-7163.MCT-09-0834
P577
2010-05-04T00:00:00Z